Contraception
Volume 64, Issue 4 , Pages 255-259 , October 2001

Involvement of endometrial membrane sulphydryl groups in blastocyst implantation: sulphydryl groups as a potential target forcontraceptive research

  • Manish Nivsarkar

      Affiliations

    • Corresponding Author InformationCorresponding author. Tel.: +91-079-743-9375; fax: +91-079-745-0449
    • Department of Pharmacology and Toxicology, B.V. Patel Pharmaceutical Education and Research Development Centre, Thaltej Gandhinagar Highway, Thaltej, Ahmedabad-380054, Gujarat, India
    • ,
  • Aditya Sethi

      Affiliations

    • Department of Pharmacology and Toxicology, B.V. Patel Pharmaceutical Education and Research Development Centre, Thaltej Gandhinagar Highway, Thaltej, Ahmedabad-380054, Gujarat, India
    • ,
  • Cherian Bapu

      Affiliations

    • Department of Pharmacology and Toxicology, B.V. Patel Pharmaceutical Education and Research Development Centre, Thaltej Gandhinagar Highway, Thaltej, Ahmedabad-380054, Gujarat, India
    • ,
  • Manoj Patel

      Affiliations

    • Department of Pharmacology and Toxicology, B.V. Patel Pharmaceutical Education and Research Development Centre, Thaltej Gandhinagar Highway, Thaltej, Ahmedabad-380054, Gujarat, India
    • ,
  • Harish Padh

      Affiliations

    • Department of Pharmacology and Toxicology, B.V. Patel Pharmaceutical Education and Research Development Centre, Thaltej Gandhinagar Highway, Thaltej, Ahmedabad-380054, Gujarat, India

References 

  1. Laloraya M. Fluidity of the phospholipid bilayer of the endometrium at the time of implantation of the blastocyst. A spin label study. Biochem Biophys Res Commun. 1990;167:561–567
  2. Laloraya M, Jain S, Thomas M, Kopergaonkar S, Kumar GP. Estrogen surge (a regulatory switch for superoxide radical generation at implantation). Biochem Mol Biol Intl. 1996;39:933–940
  3. Jain S, Saxena D, Kumar GP, Laloraya M. NADPH dependent superoxide generation in the ovary and uterus of mice during estrous cycle, and early pregnancy. Life Sci. 2000;66:1139–1146
  4. Laloraya M, Kumar GP, Laloraya MM. A possible role of superoxide anion radical in the process of blastocyst implantation in Mus musculus. Biochem Biophys Res Commun. 1989;161:762–770
  5. Thomas M, Jain S, Kumar GP, Laloraya M. Transient thiol expression and thiol disulphide cluster receptor communications (a molecular basis for blastocyst uterine interactions during implantation). Biochem Biophys Res Commun. 1994;198:150–157
  6. Sinha S, Kumar GP, Laloraya M, Warikoo D. Overexpression of superoxide dismutase and lack of surface thiols in spermatozoa (inherent defects in oligospermia). Biochem Biophys Res Commun. 1991;174:510–517
  7. Nivsarkar M, Patel RY, Mokal R. Modulation of sperm membrane conformation by pentoxyfylline in oligospermia (a biophysical investigation of sperm membrane in vitro). Biochem Biophys Res Commun. 1996;225:791–795
  8. Kumar GP, Laloraya M, Laloraya MM. Powerful anti-sperm motility action of cobaltous ion and its recovery by a sulphydryl compound. Contraception. 1990;41:633–639
  9. Nivsarkar M, Cherian B, Patel S. A regulatory role of sulphydryl groups in modulation of membrane conformation by heavy metals (sulphydryl groups as markers for infertility assessment). Biochem Biophys Res Commun. 1998;247:716–718
  10. Dutta DC. Text book of gynecology. 2nd ed.. Calcutta, India: New Central Book Agency; 1996;
  11. Stockard CR, Papinicolaou GN. The existence of a typical oestrous cycle in the guinea pig with a study of its biochemical and physiological changes. Am J Anat. 1917;22:225–283
  12. Okahwa H, Ohishi N, Yagi K. Reaction of linoleic acid hydroperoxides with thiobarbituric acids. Anal Biochem. 1979;95:351–354
  13. Marklund S, Marklund G. Involvement of the superoxide anion radical in the autooxidation of pyrogallol and a convenient assay for superoxide dismutase. Eur J Biochem. 1974;47:469–474

PII: S0010-7824(01)00254-2

Contraception
Volume 64, Issue 4 , Pages 255-259 , October 2001

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