Contraception
Volume 73, Issue 4 , Pages 415-419 , April 2006

Bleeding after medication-induced termination of pregnancy with two dosing schedules of mifepristone and misoprostol

Received 31 August 2004 ,Revised 23 July 2005 ,Accepted 8 September 2005.

References 

  1. Peyron R, Aubeny E, Targosz V, et al. Early termination of pregnancy with mifepristone (RU486) and the orally active prostaglandin misoprostol. N Engl J Med. 1993;328:1509–1513
  2. Spitz IM, Bardin CW, Benton L, Robbins A. Early pregnancy termination with mifepristone and misoprostol in the United States. N Engl J Med. 1998;338:1244–1247
  3. Ashok P, Templeton A, Wagaarachchi PT, Flett GM. Factors affecting the outcome of early medical abortion: a review of 4132 consecutive cases. Br J Obstet Gynaecol. 2002;109:1281–1289
  4. El-Refaey H, Rajasekar D, Abadía M, Calder L, Templeton A. Induction of abortion with mifepristone (RU486) and oral or vaginal misoprostol. N Engl J Med. 1995;332:983–987
  5. Schaff EA, Stadalius LS, Eisinger SH, Franks F. Vaginal misoprostol administered at home after mifepristone (RU486) for abortion. J Fam Pract. 1997;44:353–360
  6. Schaff EA, Eisinger SH, Stadalius LS, Franks P, Gore BZ, Poppema S. Low-dose mifepristone 200 mg and vaginal misoprostol for abortion. Contraception. 1999;59:1–6
  7. Schaff EA, Fielding SL, Westhoff C. Vaginal misoprostol administered 1, 2, or 3 days after mifepristone for early medical abortion: a randomized trial. JAMA. 2000;284:1948–1953
  8. Schaff EA, Fielding SL, Eisinger SH, Stadalius LS, Fuller L. Low-dose mifepristone followed by vaginal misoprostol at 48 hours for abortion up to 63 days. Contraception. 2000;61:41–46
  9. Schaff EA, Fielding SL, Westhoff C. Randomized trial of oral versus vaginal misoprostol at one day after mifepristone for early medical abortion. Contraception. 2001;64:81–85
  10. Davis A, Westhoff C, De Nonno L. Bleeding patterns after early abortion with mifepristone and misoprostol or manual vacuum aspiration. J Am Med Womens Assoc. 2000;55:141–144
  11. Bjorge L, Johnsen SL, Midboe G, et al. Early pregnancy termination with mifepristone and misoprostol in Norway. Acta Obstet Gynecol Scand. 2001;80:1056–1061
  12. DeNonno L, Westhoff C, Fielding S, Schaff EA. Timing of pain and bleeding after mifepristone-induced abortion. Contraception. 2000;62:305–309
  13. Harper C, Winikoff B, Ellertson C, Coyaji K. Blood loss with mifepristone-misoprostol abortion: measures from a trial in China, Cuba and India. Int J Gynaecol Obstet. 1998;63:39–49
  14. Creinin MD, Fox MC, Teal S, Chen AY, Schaff EA, Meyn LA. A randomized comparison of misoprostol 6 to 8 hours versus 24 hours after mifepristone for abortion. Obstet Gynecol. 2004;103:851–859

PII: S0010-7824(05)00359-8

doi: 10.1016/j.contraception.2005.09.001

Contraception
Volume 73, Issue 4 , Pages 415-419 , April 2006