Contraception
Volume 73, Issue 5 , Pages 516-519 , May 2006

Induction of second trimester abortion (12–20 weeks) with mifepristone and misoprostol: a review of 386 consecutive cases

Received 16 September 2005 ,Revised 22 November 2005 ,Accepted 13 December 2005.

References 

  1. Karim SMM, Filshie GM. Therapeutic abortion using PCF2α. Lancet. 1970;157–159
  2. Thong KJ, Baird DT. Induction of second trimester abortion with mifepristone and gemeprost. Br J Obstet Gynaecol. 1993;100:758–761
  3. Ashok PW, Templeton A. Nonsurgical mid-trimester termination of pregnancy: a review of 500 consecutive cases. Br J Obstet Gynaecol. 1999;106:706–710
  4. Gemzell-Danielsson K, Ostlund E. Termination of second trimester pregnancy with mifepristone and gemeprost. The clinical experience of 197 cases. Acta Obstet Gynaecol Scand. 2000;79:702–706
  5. El-Refaey H, Hinshaw K, Templeton A. The abortifacient effect of misoprostol in the second trimester. Hum Reprod. 1993;8:1744–1746
  6. El-Refaey H, Templeton A. Induction of abortion in the second trimester by a combination of misoprostol and mifepristone: a randomized comparison between two misoprostol regimens. Hum Reprod. 1995;10:475–478
  7. Collins PW. Misoprostol: discovery, development, and clinical applications. Med Res Rev. 1990;10:149–172
  8. McKinley C, Thong KJ, Baird DT. The effect of dose of mifepristone and gestation on the efficacy of medical abortion with mifepristone and misoprostol. Hum Reprod. 1993;8:1502–1505
  9. Urquhart DR, Templeton A. The use of mifepristone prior to prostaglandin induced mid-trimester termination. Hum Reprod. 1990;5:883–886
  10. Rodger MT, Baird DT. Pre-treatment with mifepristone (RU 486) reduces interval between prostaglandin administration and expulsion in second trimester abortion. Br J Obstet Gynaecol. 1990;97:41–45
  11. Webster D, Penney GC, Templeton A. A comparison of 600 and 200 mg mifepristone prior to second trimester abortion with prostaglandin misoprostol. Br J Obstet Gynaecol. 1996;103:706–709
  12. Thong KJ, Baird DT. Induction of abortion with mifepristone and misoprostol in early pregnancy. Br J Obstet Gynaecol. 1992;99:1004–1007
  13. Tang OS, Thong KJ, Baird DT. Second trimester medical abortion with mifepristone and gemeprost: a review of 956 cases. Contraception. 2001;64:29–32
  14. Bartley J, Tong S, Everington D, Baird DT. Parity is a major determinant of success rate in medical abortion: a retrospective analysis of 3161 consecutive cases of early medical abortion treated with reduced doses of mifepristone and vaginal gemeprost. Contraception. 2000;62:297–303
  15. Ashok PW, Penney GC, Flett GMM, Templeton A. An effective regimen for early medical abortion: a report of 2000 consecutive cases. Hum Reprod. 1998;13:2962–2965

PII: S0010-7824(05)00483-X

doi: 10.1016/j.contraception.2005.12.004

Contraception
Volume 73, Issue 5 , Pages 516-519 , May 2006

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