Contraception
Volume 74, Issue 1 , Pages 42-44 , July 2006

Evidence for shortening the time interval of prostaglandin after mifepristone for medical abortion

  • Eric Schaff

      Affiliations

    • Corresponding Author InformationWilmington, Delaware, 19801 USA. Tel.: +1 585 233 2124; fax: +1 866 585 0371.

Received 10 February 2006 ,Revised 3 March 2006 ,Accepted 10 March 2006.

References 

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  3. Heikinheimo O, Lahteenmaki PL, Koivunen E, et al. Metabolism and serum binding of RU 486 in women after various single doses. Hum Reprod. 1987;2:379–385
  4. Heikinheimo O, Kontula K, Croxatto H, et al. Plasma concentrations and receptor binding of RU 486 and its metabolites in humans. J Steroid Biochem. 1987;26:279–284
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  6. Mifegyne . http://www.medsafe.govt.nz/profs/Datasheet/m/Mifegynetab.htm
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  8. Carbonell J, Carbonell JL, Varela L, et al. The use of misoprostol for abortion at < or = 9 weeks' gestation. Eur J Contracpt Reprod Health Care. 1997;2:181–185
  9. Carbonell JL, Rodriguez J, Aragon S, et al. Vaginal misoprostol 1000 μg for early abortion. Contraception. 2001;63:131–136
  10. Carbonell JL, Rodriguez J, Velazco A, et al. Oral and vaginal misoprostol 800 μg every 8 h for early abortion. Contraception. 2003;67:457–462
  11. Kulier R, Gulmezoglu AM, Hofmeyr GJ, et al. Medical methods for first trimester abortion. Cochrane Database Syst Rev. 2004;(2):CD002855
  12. Schaff EA, Fielding SL, Westhoff C, et al. Vaginal misoprostol administered 1, 2, or 3 days after mifepristone for early medical abortion: a randomized trial. JAMA. 2000;284:1948–1953
  13. Sandstrom O, Brooks L, Schantz A, et al. Interruption of early pregnancy with mifepristone in combination with gemeprost. Acta Obstet Gynecol Scand. 1999;78:806–809
  14. Creinin MD, Schwartz JL, Pymar HC, et al. Efficacy of mifepristone followed on the same day by misoprostol for early termination of pregnancy: report of a randomised trial. BJOG. 2001;108:469–473
  15. Schaff EA, Fielding SL, Westhoff C. Randomized trial of oral versus vaginal misoprostol at one day after mifepristone for early medical abortion. Contraception. 2001;64:81–85
  16. Creinin MD, Fox MC, Teal S, et al. A randomized comparison of misoprostol 6 to 8 hours versus 24 hours after mifepristone for abortion. Obstet Gynecol. 2004;103(5 Pt 1):851–859

PII: S0010-7824(06)00094-1

doi: 10.1016/j.contraception.2006.03.014

Contraception
Volume 74, Issue 1 , Pages 42-44 , July 2006

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