Contraception
Volume 77, Issue 4 , Pages 294-298 , April 2008

High prevalence of Mycoplasma genitalium in women presenting for termination of pregnancy

  • Beverley A. Lawton

      Affiliations

    • Women's Health Research Centre, Department of Primary Health Care and General Practice, Wellington School of Medicine and Health Sciences, PO Box 7343, Wellington South, New Zealand
    • Corresponding Author InformationCorresponding author. Tel.: +64 4 385 5995x4893; fax: +64 4 385 5473.
    • ,
  • Sally B. Rose

      Affiliations

    • Women's Health Research Centre, Department of Primary Health Care and General Practice, Wellington School of Medicine and Health Sciences, PO Box 7343, Wellington South, New Zealand
    • ,
  • Collette Bromhead

      Affiliations

    • Molecular Biology Department, Aotea Pathology, Wellington, New Zealand
    • ,
  • Louise A. Gaitanos

      Affiliations

    • Molecular Biology Department, Aotea Pathology, Wellington, New Zealand
    • ,
  • E. Jane MacDonald

      Affiliations

    • WIPA Wellington Sexual Health Service, Newtown, Wellington
    • ,
  • Kim A. Lund

      Affiliations

    • Wellington Hospital, Capital and Coast District Health Board, New Zealand

Received 5 October 2007 ,Revised 20 December 2007 ,Accepted 21 December 2007.

References 

  1. Abortion Supervisory Committee . Report of the Abortion Supervisory Committee 2005. In: Presented to the House of Representatives pursuant to Section 39 of the Contraception, Sterilisation and Abortion Act 1977: New Zealand. 2006;
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  13. Haggerty CL, Totten PA, Astete SG, Ness RB. Mycoplasma genitalium among women with nongonococcal nonchlamydial pelvici nflammatory disease. Infect Dis Obstet Gynecol. 2006;2006:1–5[ID 30184]
  14. Perez G, Skurnick JH, Denny TN, et al. Herpes simplex type II and Mycoplasma genitalium as risk factors for heterosexual HIV transmission: report from the heterosexual HIV transmission study. [see comment] Int J Infect Dis. 1998;3(1):5–11
  15. Crotchfelt KA, Welsh LE, DeBonville D, Rosenstraus M, Quinn TC. Detection of Neisseria gonorrhoeae and Chlamydia trachomatis in genitourinary specimens from men and women by a coamplification PCR assay. J Clin Microbiol. 1997;35:1536–1540
  16. Schachter J, McCormack WM, Chernesky MA, et al. Vaginal swabs are appropriate specimens for diagnosis of genital tract infection with Chlamydia trachomatis. J Clin Microbiol. 2003;41:3784–4739
  17. Jensen JS. Mycoplasma genitalium infections. Diagnosis, clinical aspects, and pathogenesis. Danish Med Bull. 2006;53:1–27
  18. Labbe AC, Frost E, Deslandes S, Mendonca AP, Alves AC, Pepin J. Mycoplasma genitalium is not associated with adverse outcomes of pregnancy in Guinea-Bissau. Sex Transm Infect. 2002;78:289–291
  19. Lu GC, Schwebke JR, Duffy LB, et al. Midtrimester vaginal Mycoplasma genitalium in women with subsequent spontaneous preterm birth. Am J Obstet Gynecol. 2001;185:163–165
  20. Edwards RK, Ferguson RJ, Reyes L, Brown M, Theriaque DW, Duff P. Assessing the relationship between preterm delivery and various microorganisms recovered from the lower genital tract. J Matern-Fetal Neonatal Med. 2006;19:357
  21. Kataoka S, Yamada T, Chou K, et al. Association between preterm birth and vaginal colonization by mycoplasmas in early pregnancy. J Clin Microbiol. 2006;44:51–55
  22. Centers for Disease Control and Prevention: Sexually Transmitted Diseases Treatment Guidelines 2002. Morb Mortal Wkly Rep. 2002;51(No. RR-6):1–78
  23. Rose SB, Lawton BA, Bromhead C, MacDonald J, Lund KA. Self-obtained vaginal swabs for PCR Chlamydia testing: a practical alternative. Aust N Z J Obstet Gynaecol. 2007;47:415
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  26. Crowley T, Lowb N, Turnerc A, Harvey I, Bidgoodd K, Horner P. Antibiotic prophylaxis to prevent post-abortal upper genital tract infection in women with bacterial vaginosis: randomised controlled trial. Br J Obstet Gynaecol. 2001;108:396–402
  27. Falk L, Fredlund H, Jensen JS. Tetracycline treatment does not eradicate Mycoplasma genitalium. Sex Transm Infect. 2003;79:318–319
  28. Bradshaw CS, Jensen JS, Tabrizi SN, et al. Azithromycin failure in Mycoplasma genitalium urethritis. Emerg Infect Dis. 2006;12:1149–1152

☆ This study was funded by a grant from the University of Otago and from ISTAR (a nonprofit organization that imports and distributes mifepristone in New Zealand). The authors would like to thank the women who participated in the study and the staff at the Wellington Hospital TOP unit and Aotea Pathology for their assistance with this study. We gratefully acknowledge the assistance of Dr Christoph Noppen, Viollier AG, Basel, Switzerland, for the MG297 assay, and Roche Diagnostics New Zealand for supplying PCR reagents.

PII: S0010-7824(08)00002-4

doi: 10.1016/j.contraception.2007.12.002

Contraception
Volume 77, Issue 4 , Pages 294-298 , April 2008

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