Contraception
Volume 78, Issue 4, Supplement , Pages S23-S27, October 2008

Male contraception: what is on the horizon?

  • Diana Blithe

      Affiliations

    • Corresponding Author InformationTel.: +1 301 435 6990; fax: +1 301 480 1972.

Contraception and Reproductive Health Branch, Center for Population Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892, USA

Received 20 March 2008; accepted 20 March 2008. published online 11 August 2008.

Abstract 

Male contraception remains an important area of research. Methods can inhibit sperm production or can be targeted to inhibit sperm functions such as motility, orientation or interaction with the egg. Hormonal methods appear to be safe and effective in proof of concept studies but efforts are underway to improve delivery options or lead time until full efficacy is achieved. Nonhormonal methods are based on numerous targets that impact sperm production or function. Several agents that inhibit the sperm-specific or testis-specific targets have been identified and studies in animals have shown promising results.

Keywords: Male contraception, Hormonal approach, Spermatogenesis, Sperm-specific nonhormonal targets

To access this article, please choose from the options below

Login to an existing account or Register a new account.

  • Purchase this article for 31.50 USD (You must login/register to purchase this article)

    Online access for 24 hours. The PDF version can be downloaded as your permanent record.

  • Subscribe to this title

    Get unlimited online access to this article and all other articles in this title 24/7 for one year.

  • Claim access now

    For current subscribers with Society Membership or Account Number.

  • Visit SciVerse ScienceDirect to see if you have access via your institution.
 

 Author Disclosure: Diana Blithe does not report any conflicts of interest with the sponsor of this supplement article or products discussed in this article.

PII: S0010-7824(08)00276-X

doi:10.1016/j.contraception.2008.03.018

Contraception
Volume 78, Issue 4, Supplement , Pages S23-S27, October 2008

Article Tools

* Image Usage & Resolution