« Previous
Next »
Contraception
Volume 78, Issue 4,
Supplement
, Pages S23-S27
, October 2008
Male contraception: what is on the horizon?
References
- . Maternal mortality in 2005. Geneva, Switzerland: World Health Organization; 2007;
- . Reducing unintended pregnancy in the United States. Contraception. 2008;77:1–5
- . Attitudes toward male fertility control: results of a multinational survey on four continents. Hum Reprod. 2005;20:549–556
- In: Nass SJ, Strauss JF editor. New frontiers in contraceptive research: a blueprint for action. Washington, DC: The National Academies Press; 2004;
- . Update in andrology. J Clin Endocrinol Metab. 2007;92:4505–4511
- . Hormonal approaches to male contraception: approaching reality. Mol Cell Endocrinol. 2006;250:2–7
- . Male contraception: a realistic option?. Eur J Contracept Reprod Health Care. 2006;11:69–80
- . Male hormonal contraception: concept proven, product in sight?. Hum Reprod Update. 2006;12:463–482
- Intratesticular testosterone concentrations comparable with serum levels are not sufficient to maintain normal sperm production in men receiving a hormonal contraceptive regimen. J Androl. 2004;25:931–938
- . A single dose of the potent gonadotropin-releasing hormone antagonist acyline suppresses gonadotropins and testosterone for 2 weeks in healthy young men. J Clin Endocrinol Metab. 2004;89:5959–5965
- Norethisterone enanthate plus testosterone undecanoate for male contraception: effects of various injection intervals on spermatogenesis, reproductive hormones, testis, and prostate. J Clin Endocrinol Metab. 2005;90:2005–2014
- . Expanding the therapeutic use of androgens via selective androgen receptor modulators (SARMs). Drug Discov Today. 2007;12:241–248
- . Dimethandrolone undecanoate: a new potent orally active androgen with progestational activity. Endocrinology. 2006;147:3016–3026
- . Evidence for tissue selectivity of the synthetic androgen 7-alpha-methyl-19-nortestosterone in hypogonadal men. J Clin Endocrinol Metab. 2003;88:2784–2793
- . The A-type cyclins and the meiotic cell cycle in mammalian male germ cells. Int J Androl. 2004;27:192–199
- . Retinoid signaling during spermatogenesis as revealed by genetic and metabolic manipulations of retinoic acid receptor alpha. Soc Reprod Fertil Suppl. 2007;63:11–23
- Development of l-CDB-4022 as a nonsteroidal male oral contraceptive: induction and recovery from severe oligospermia in the adult male cynomolgus monkey (Macaca fascicularis). Endocrinology. 2007;148:1784–1796
- . A male contraceptive targeting germ cell adhesion. Nat Med. 2006;12:1323–1328
- . A novel potent indazole carboxylic acid derivative blocks spermatogenesis and is contraceptive in rats after a single oral dose. Biol Reprod. 2008;78:1127–1138
- . Targeted and reversible disruption of the blood–testis barrier by an FSH mutant–occludin peptide conjugate. FASEB J. 2007;21:438–448
- . All four CatSper ion channel proteins are required for male fertility and sperm cell hyperactivated motility. Proc Natl Acad Sci U S A. 2007;104:1219–1223
- . KSper, a pH-sensitive K+ current that controls sperm membrane potential. Proc Natl Acad Sci U S A. 2007;104:7688–7692
- . Physiological volume regulation by spermatozoa. Mol Cell Endocrinol. 2006;250:98–105
- Postnatal expression of aquaporins in epithelial cells of the rat epididymis. Biol Reprod. 2006;74:427–438
- . The Na,K-ATPase alpha4 isoform from humans has distinct enzymatic properties and is important for sperm motility. Mol Hum Reprod. 2006;12:565–576
- . Na+/K+ATPase as a signaling molecule during bovine sperm capacitation. Biol Reprod. 2006;75:308–317
- . Odorant receptors and olfactory-like signaling mechanisms in mammalian sperm. Mol Cell Endocrinol. 2006;250:128–136
- . Proteins associated with soluble adenylyl cyclase in sea urchin sperm flagella. Cell Motil Cytoskeleton. 2006;63:582–590
- . Insights into sperm cell motility signaling through sNHE and the CatSpers. Mol Cell Endocrinol. 2006;250:84–92
- A K+-selective cGMP-gated ion channel controls chemosensation of sperm. Nat Cell Biol. 2006;8:1149–1154
- Ion channels in sperm motility and capacitation. Soc Reprod Fertil Suppl. 2007;65:229–244
- . Sperm activation: role of reactive oxygen species and kinases. Biochim Biophys Acta. 2008;1784:106–115
- . Multiple glycolytic enzymes are tightly bound to the fibrous sheath of mouse spermatozoa. Biol Reprod. 2006;75:270–278
- Glyceraldehyde 3-phosphate dehydrogenase-S, a sperm-specific glycolytic enzyme, is required for sperm motility and male fertility. Proc Natl Acad Sci USA. 2004;101:16501–16506
- Testosterone gel combined with depomedroxyprogesterone acetate is an effective male hormonal contraceptive regimen and is not enhanced by the addition of a GnRH antagonist. J Clin Endocrinol Metab. 2006;91:4374–4380
Author Disclosure: Diana Blithe does not report any conflicts of interest with the sponsor of this supplement article or products discussed in this article.
PII: S0010-7824(08)00276-X
doi: 10.1016/j.contraception.2008.03.018
« Previous
Next »
Contraception
Volume 78, Issue 4,
Supplement
, Pages S23-S27
, October 2008
