Contraception
Volume 79, Issue 6 , Pages 469-478 , June 2009

Effects of doxycycline on serum and endometrial levels of MMP-2, MMP-9 and TIMP-1 in women using a levonorgestrel-releasing subcutaneous implant

  • Shumei Zhao

      Affiliations

    • Department of Obstetrics and Gynecology, CONRAD Clinical Research Center, Jones Institute for Reproductive Medicine, Eastern Virginia Medical School, Norfolk, VA 23507, USA
    • Corresponding Author InformationCorresponding author. Tel.: +1 757 446 7056; fax: +1 757 446 8998.
  • ,
  • Chainarong Choksuchat

      Affiliations

    • Department of Obstetrics and Gynecology, Prince of Songkla University, Songkla, Thailand 90110
  • ,
  • Yueqin Zhao

      Affiliations

    • Epidemiology and Biostatistics Core, Graduate Program of Public Health, Eastern Virginia Medical School, Norfolk, VA 23507, USA
  • ,
  • Susan A. Ballagh

      Affiliations

    • Department of Obstetrics and Gynecology, CONRAD Clinical Research Center, Jones Institute for Reproductive Medicine, Eastern Virginia Medical School, Norfolk, VA 23507, USA
  • ,
  • George A. Kovalevsky

      Affiliations

    • Department of Obstetrics and Gynecology, CONRAD Clinical Research Center, Jones Institute for Reproductive Medicine, Eastern Virginia Medical School, Norfolk, VA 23507, USA
  • ,
  • David F. Archer

      Affiliations

    • Department of Obstetrics and Gynecology, CONRAD Clinical Research Center, Jones Institute for Reproductive Medicine, Eastern Virginia Medical School, Norfolk, VA 23507, USA

Received 5 November 2008 ,Revised 22 December 2008 ,Accepted 23 December 2008.

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 The research was supported by NIH Grant R01 HD43175-01.

☆☆ Dr. Shumei Zhao, Dr. Chainarong Choksuchat, Ms. Yueqin Zhao and Dr. George Kovalevsky have no conflicts of interest. Dr. David Archer is a paid consultant for Abbott Laboratories, Agile Therapeutics, Bayer Healthcare, Berlex, ConCert Pharmaceutical, Novo Nordisk, Radius, Schering Plough, Warner Chilcott and Wyeth Laboratories; he has Industry-Supported Research from Bayer Healthcare, Duramed, Organon-Schering Plough, Solvay, Warner Chilcott and Wyeth Laboratories; he receives Direct Industry Lecture Fees from Novo Nordisk, Organon, Schering Plough, Solvay, Upsher-Smith Laboratories and Wyeth Laboratories. Dr. Susan Ballagh is a paid consultant for Contraception Online, Gerson-Lehrman Group, Organon and Wyeth Laboratories; she has Industry-Support Research from Duramed Research, Bayer Healthcare, Conceptus, Pfizer, Organon, Warner-Chilcott and Wyeth Laboratories; she receives Direct Industry Lecture Fees from ARHP, Cardinal Health, Organon and Wyeth Laboratories.

PII: S0010-7824(08)00579-9

doi: 10.1016/j.contraception.2008.12.010

Contraception
Volume 79, Issue 6 , Pages 469-478 , June 2009