Contraception
Volume 79, Issue 6 , Pages 445-451 , June 2009

Pharmacy worker practices related to use of misoprostol for abortion in one Mexican state

  • Deborah L. Billings

      Affiliations

    • Independent Consultant, Columbia, SC 29205, USA
    • Corresponding Author InformationCorresponding author. Tel.: +1 803 223 9418.
    • The author was a Senior Research Associate at Ipas at the time of research.
  • ,
  • Dilys Walker

      Affiliations

    • National Institute of Public Health (Instituto Nacional de Salud Pública), Cuernavaca, Morelos 62508, Mexico
  • ,
  • Guadalupe Mainero del Paso

      Affiliations

    • CIDHAL, Communication and Exchange for Human Development in Latin America (Comunicación e Intercambio para el desarrollo humano en América Latina), Cuernavaca, Morelos 62440, Mexico
  • ,
  • Kathryn Andersen Clark

      Affiliations

    • Ipas, Chapel Hill, NC 27516, USA
  • ,
  • Ila Dayananda

      Affiliations

    • Brigham and Women's Hospital, Boston, MA 02115, USA

Received 21 May 2008 ,Revised 23 December 2008 ,Accepted 23 December 2008.

References 

  1. PATH (Program for Appropriate Technology in Health) . Increasing access to reproductive health services through pharmacists. Outlook. 2004;21:1–6
  2. Goel P, Ross-Degnan D, Berman P, Soumeri S. Retail pharmacies in developing countries: a behavior and intervention framework. Soc Sci Med. 1996;42:1155–1161
  3. Leyva-Flores R, Bronfman M, Erviti-Erice J. Clientes ficticios en farmacias: conducta prescriptiva de los dependientes de farmacias. J Social Adm Pharm. 2000;17:151–158
  4. Mayhew S, Khonde N, Pépin J, Adjei S. Pharmacists' role in managing sexually transmitted infections: policy issue and options for Ghana. Health Policy Plann. 2001;16:152–160
  5. Finger WR. Commercial sector can improve access. Network. 1998;18:12
  6. Blanchard K, Harrison T, Sello M. Pharmacists' knowledge and perceptions of emergency contraception pills in Soweto and the Johannesburg central business district, South Africa. Int Fam Plann Perspect. 2005;31:172–178
  7. Igun UA. Reported and actual prescription of oral rehydration therapy for childhood diarrhoeas by retail pharmacists in Nigeria. Soc Sci Med. 1994;39:797–806
  8. Ramos MC, da Silva RD, Gobbato RO, et al. Pharmacy clerks' prescribing practices for STD patients in Porto Alegre, Brazil: missed opportunities for improving STD control. Int J STD AIDS. 2004;15:333–336
  9. Leyva-Flores R, Erviti-Erice J, Ramsey J, Gasman N. Medical drug utilization patterns for febrile patients in rural areas of Mexico. J Clin Epidemiol. 1997;50:329–335
  10. Drug Utilization Research Group. Multicenter study on self-medication and self-prescription in six Latin American countries. Clin Pharmacol Ther. 1997;61:488–493
  11. Turner A, Ellertson C, Thomas S, García S. Diagnosis and treatment of presumed STIs at Mexican pharmacies: survey results from a random sample of Mexico City pharmacy attendants. Sex Transm Infect. 2003;79:224–228
  12. Chalker J, Chuc NT, Falkenberg T, Tomson G. STD management by private pharmacies in Hanoi: practice and knowledge of drug sellers. Sex Transm Infect. 2000;76:299–302
  13. Bista PP, Chaudhary P, Slanger TE, Khan MH. The practice of STI treatment among chemists and druggists in Pokhara, Nepal. Sex Transm Infect. 2002;78:223
  14. Garcia P, Hughes J, Carcomo C, Holmes K. Training pharmacy workers in recognition, management, and prevention of STDs: district-randomized controlled trial. WHO. 2003;81:806–814
  15. Costa SH. Commercial availability of misoprostol and induced abortion in Brazil. Int J Gynaecol Obstet. 1998;63:S131–S139
  16. Kroeger A, Ochoa H, Arana B, Diaz A, Rizzo N, Flores W. Inadequate drug advice in the pharmacies of Guatemala and Mexico: the scale of the problem and explanatory factors. Ann Trop Med Parasitol. 2001;95:605–616
  17. Secretaría de Salud . Encuesta Nacional de Salud II. México, DF: Secretaría de Salud; 1994;
  18. Angeles P, Medina M, Molina JF. Automedicación en población urbana de Cuernavaca, Morelos. Salud Pública Méx. 1992;34:487–590
  19. WHO . Unsafe abortion: global and regional estimates of incidence of unsafe abortion and associated mortality in 2003. 5th ed.. Geneva, Switzerland: WHO; 2007;
  20. Sedgh G, Henshaw S, Singh S, Ahman E, Shah IH. Induced abortion: estimated rates and trends worldwide. Lancet. 2007;370:1338–1345
  21. Schiavon R, Polo G, Troncoso E. Hoja Informativa. Aportes para el debate sobre la despenalización del aborto [accessed on March 18, 2008]. Available from: http://www.ipas.org/Publications/asset_upload_file73_3073.pdf2008;
  22. Coelho HL, Teixeira AC, Santos AP, et al. Misoprostol and illegal abortion in Fortaleza, Brazil. Lancet. 1993;341:1261–1263
  23. Coelho HL, Teixeira AC, Cruz Mde F, et al. Misoprostol: the experience of women in Fortaleza, Brazil. Contraception. 1994;49:202–220
  24. Barbosa RM, Arilha M. The Brazilian experience with misoprostol. Stud Fam Plann. 1993;24:236–240
  25. Cohen J, Ortíz O, Llaguno SE, Goodyear L, Billings D, Martínez I. Reaching women with instructions on misoprostol use in a Latin American country. Reprod Health Matters. 2005;13:84–92
  26. Lara D, Abuabara K, Grossman D, Diaz-Olavarrieta C. Pharmacy provision of medical abortifacients in a Latin American City. Contraception. 2006;74:394–399
  27. Pick S, Givaudan M, Cohen S, Alvarez M, Collado ME. Pharmacists and market herb vendors: abortifacient providers in Mexico City. In:  Mundigo AI,  Indriso C editor. Abortion in the developing world. New Delhi: Vistaar Publications; 1999;p. 293–310
  28. Madden JM, Quick J, Ross-Degnan D, Kafle KK. Undercover careseekers: simulated clients in the study of health provider behavior in developing countries. Soc Sci Med. 1997;45:1465–1482
  29. Huntington D, Schuler SR. The simulated client method: evaluating client–provider interactions in family planning clinics. Stud Fam Plann. 1993;24:187–193
  30. Gemzell-Danielsson K, Marions L, Rodriguez A, Spur BW, Wong PY, Bygdeman M. Comparison between oral and vaginal administration of misoprostol on uterine contractility. Obstet Gynecol. 1999;93:275–280
  31. Blanchard K, Shochet T, Coyaji K, Ngoc NTN, Winikoff B. Misoprostol alone for early abortion: an evaluation of seven potential regimens. Contraception. 2005;72:91–97
  32. Norman JE, Thong KJ, Baird DT. Uterine contractility and induction of abortion in early pregnancy by misoprostol and mifepristone. Lancet. 1991;338:1233–1236
  33. Carbonell JL, Varela L, Velazco A, Fernández C. The use of misoprostol for termination of early pregnancy. Contraception. 1997;55:165–168
  34. Jain JK, Meckstroth KR, Michell DR. Early pregnancy termination with intravaginally administered sodium chloride solution-moistened misoprostol tablets: historical comparison with mifepristone and oral misoprostol. Am J Obstet Gynecol. 1999;181:1386–1391
  35. Jain JK, Dutton C, Harwood B, Meckstroth KR, Michell DR. A prospective randomized, double-blinded, placebo controlled trial comparing mifepristone and vaginal misoprostol to vaginal misoprostol alone for elective termination of pregnancy. Hum Reprod. 2002;17:1477–1482
  36. Carbonell JL, Rodriguez J, Aragon S, et al. Vaginal misoprostol 1000 micrograms for early abortion. Contraception. 2001;63:131–136
  37. Von Hertzen H, Piaggio G, Nguyen TMH, et al. Efficacy of two intervals and two routes of administration of misoprostol for termination of early pregnancy: a randomised controlled equivalence trial. Lancet. 2007;369:1938–1946
  38. http://www.misoprostol.com.mx/index.htm. Accessed on May 10, 2008.
  39. Secretaría de Salud. Hacía una política farmacéutica integral para México. 2005. Sistema Federal Sanitario: Comisíon Federal para la Protección contra Riesgos Sanitarios. http://www.cofepris.gob.mx. [accessed on May 10, 2008].
  40. Maderas NM, Landau SC, Taylor-McGhee B. Editorial: The continuum of care: a case for pharmacists as key members of a reproductive health team. Contraception. 2008;77:139–142

 The authors would like to recognize the Swedish International Development Agency for funding this study through a grant to Ipas.

PII: S0010-7824(08)00580-5

doi: 10.1016/j.contraception.2008.12.011

Contraception
Volume 79, Issue 6 , Pages 445-451 , June 2009