Contraception
Volume 81, Issue 3 , Pages 245-248 , March 2010

Antimullerian hormone and obesity: insights in oral contraceptive users

  • Anne Z. Steiner

      Affiliations

    • Department of Obstetrics and Gynecology, University of North Carolina, Chapel Hill, NC 27599, USA
    • Corresponding Author InformationCorresponding author.
    • ,
  • Frank Z. Stanczyk

      Affiliations

    • Department of Obstetrics and Gynecology, University of Southern California, Los Angeles, CA 90033, USA
    • ,
  • Stan Patel

      Affiliations

    • Department of Obstetrics and Gynecology, University of Southern California, Los Angeles, CA 90033, USA
    • ,
  • Alison Edelman

      Affiliations

    • Department of Obstetrics and Gynecology, Oregon Health Science University (OHSU), Portland, OR 97239, USA

Received 15 May 2009 ,Revised 24 September 2009 ,Accepted 6 October 2009.

References 

  1. van Rooij IA, Broekmans FJ, Scheffer GJ, et al. Serum antimullerian hormone levels best reflect the reproductive decline with age in normal women with proven fertility: a longitudinal study. Fertil Steril. 2005;83:979–987
  2. van Rooij IA, Broekmans FJ, te Velde ER, et al. Serum anti-Mullerian hormone levels: a novel measure of ovarian reserve. Hum Reprod. 2002;17:3065–3071
  3. Fanchin R, Taieb J, Lozano DH, Ducot B, Frydman R, Bouyer J. High reproducibility of serum anti-Mullerian hormone measurements suggests a multi-staged follicular secretion and strengthens its role in the assessment of ovarian follicular status. Hum Reprod. 2005;20:923–927
  4. Hehenkamp WJ, Looman CW, Themmen AP, de Jong FH, Te Velde ER, Broekmans FJ. Anti-Mullerian hormone levels in the spontaneous menstrual cycle do not show substantial fluctuation. J Clin Endocrinol Metab. 2006;91:4057–4063
  5. Somunkiran A, Yavuz T, Yucel O, Ozdemir I. Anti-Mullerian hormone levels during hormonal contraception in women with polycystic ovary syndrome. Eur J Obstet Gynecol Reprod Biol. 2007;134:196–201
  6. Visser JF, de Jong FH, Laven JSE, Themmen APN. Anti-Mullerian hormone: a new marker for ovarian function. Reproduc. 2006;131:1–9
  7. Freeman EW, Gracia CR, Sammel MD, Lin H, Lim LC, Strauss JF. Association of anti-mullerian hormone levels with obesity in late reproductive-age women. Fertil Steril. 2007;87:101–106
  8. Su HI, Sammel MD, Freeman EW, Lin H, Deblasis T, Gracia CR. Body size affects measures of ovarian reserve in late reproductive age women. Menopause. 2008;15:857–861
  9. Edelman AB, Carlson NE, Cherala G, et al. Impact of obesity on oral contraceptive pharmacokinetics and hypothalamic-pituitary-ovarian activity. Contraception. 2009;80:119–127
  10. Arbo E, Vetori DV, Jimenez MF, Freitas FM, Lemos N, Cunha-Filho JS. Serum anti-mullerian hormone levels and follicular cohort characteristics after pituitary suppression in the late luteal phase with oral contraceptive pills. Hum Reprod. 2007;22:3192–3196
  11. Streuli I, Fraisse T, Pillet C, Ibecheole V, Bischof P, de Ziegler D. Serum antimullerian hormone levels remain stable throughout the menstrual cycle and after oral or vaginal administration of synthetic sex steroids. Fertil Steril. 2008;90:395–400
  12. van Disseldorp J, Faddy MJ, Themmen AP, et al. Relationship of serum antimullerian hormone concentration to age at menopause. J Clin Endocrinol Metab. 2008;93:2129–2134
  13. Grossman MP, Nakajima ST, Fallat ME, Siow Y. Mullerian-inhibiting substance inhibits cytochrome P450 aromatase activity in human granulosa lutein cell culture. Fertil Steril. 2008;89:1364–1370
  14. Weenen C, Laven JS, Von Bergh AR, et al. Anti-Mullerian hormone expression pattern in the human ovary: potential implications for initial and cyclic follicle recruitment. Mol Hum Reprod. 2004;10:77–83
  15. Andersen CY, Byskov AG. Estradiol and regulation of anti-Mullerian hormone, inhibin-A, and inhibin-B secretion: analysis of small antral and preovulatory human follicles' fluid. J Clin Endocrinol Metab. 2006;91:4064–4069
  16. Andersen CY, Lossl K. Increased intrafollicular androgen levels affect human granulosa cell secretion of anti-Mullerian hormone and inhibin-B. Fertil Steril. 2008;89:1760–1765
  17. Ledoux S, Campos DB, Lopes FL, Dobias-Goff M, Palin MF, Murphy BD. Adiponectin induces periovulatory changes in ovarian follicular cells. Endocrinol. 2006;147:5178–5186
  18. Arita Y, Kihara S, Ouchi N, et al. Paradoxical decrease of an adipose-specific protein, adiponectin, in obesity. Biochem Biophys Res Commun. 1999;257:79–83
  19. Gracia CR, Freeman EW, Sammel MD, Lin H, Nelson DB. The relationship between obesity and race on inhibin B during the menopause transition. Menopause. 2007;12:559–566

☆ Financial support: HD 01243-03 Women's Reproductive Health Research Fellow (NICHD K-12), PHS Grant 5 M01 RR000334, 1 R03 HD 053611-01, UNC WRHR HD 050113-02 and the University of North Carolina: University Research Council Grant.

PII: S0010-7824(09)00450-8

doi: 10.1016/j.contraception.2009.10.004

Contraception
Volume 81, Issue 3 , Pages 245-248 , March 2010

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