Contraception
Volume 82, Issue 2 , Pages 155-159 , August 2010

Effects of sex hormones in oral contraceptives on the female sexual function score: a study in German female medical students

  • Markus Wallwiener

      Affiliations

    • Department of OB/GYN, University Hospital Heidelberg, University of Heidelberg, 69115 Heidelberg, Germany
    • Corresponding Author InformationCorresponding author. Fax: +49 (0) 89 387 99588.
    • Authors have contributed equally.
    • ,
  • Lisa-Maria Wallwiener

      Affiliations

    • Department of OB/GYN, University Hospital Heidelberg, University of Heidelberg, 69115 Heidelberg, Germany
    • Authors have contributed equally.
    • ,
  • Harald Seeger

      Affiliations

    • Department of OB/GYN, University Hospital Tuebingen, University of Tuebingen, 72076 Tuebingen, Germany
    • ,
  • Alfred O. Mueck

      Affiliations

    • Department of OB/GYN, University Hospital Tuebingen, University of Tuebingen, 72076 Tuebingen, Germany
    • ,
  • Stephan Zipfel

      Affiliations

    • Department of Psychosomatic Medicine and Psychotherapy, University of Tuebingen, 72076 Tuebingen, Germany
    • ,
  • Johannes Bitzer

      Affiliations

    • Department of OB/GYN, University Hospital Basel, University of Basel, 4056 Basel, Switzerland
    • ,
  • Christian W. Wallwiener

      Affiliations

    • Department of OB/GYN, University Hospital Tuebingen, University of Tuebingen, 72076 Tuebingen, Germany

Received 22 October 2009 ,Revised 23 December 2009 ,Accepted 30 December 2009.

References 

  1. Goldstein I, Traish A, Munarriz R. The role of sex steroid hormones in female sexual function and dysfunction. Clin Obstet Gynecol. 2004;47:471–484
  2. Kuhl H. Pharmacology of estrogens and progestogens: influence of different routes of administration. Climacteric. 2005;8(Suppl 1):3–63
  3. Bitzer J. Contraception and sexuality. Ther Umsch. 1994;51:110–114
  4. Davis AR, Castano PM. Oral contraceptives and libido in women. Annu Rev Sex Res. 2004;15:297–320
  5. Witting K, Santtila P, Jern P, et al. Evaluation of the Female Sexual Function Index in a population based sample from Finland. Arch Sex Behav. 2008;37:912–924
  6. Wiegratz I, Kutschera E, Lee JH, et al. Effect of four different oral contraceptives on various sex hormones and serum-binding globulins. Contraception. 2003;67:25–32
  7. Rosen R, Brown C, Heiman J, et al. The Female Sexual Function Index (FSFI): a multidimensional self-report instrument for the assessment of female sexual function. J Sex Marital Ther. 2000;26:191–208
  8. Daker-White G. Reliable and valid self-report outcome measures in sexual (dys)function: a systematic review. Arch Sex Behav. 2002;31:197–209
  9. Berner MM, et al. Validity and reliability of the German Female Sexual Function Index (FSFI-d). Geburtsh Frauenheilk. 2004;64:293–303
  10. Korda JB. Female sexual dysfunction. Urologe. 2008;47:77–91
  11. Goldstein IMC, Meston CR, Davis SR, et al. Women's sexual function and dysfunction: study, diagnosis and treatment. New York: Taylor & Francis; 2006;
  12. Bhasin S, Enzlin P, Coviello A, Basson R. Sexual dysfunction in men and women with endocrine disorders. Lancet. 2007;369:597–611
  13. Graham CA, Bancroft J, Doll HA, Greco T, Tanner A. Does oral contraceptive-induced reduction in free testosterone adversely affect the sexuality or mood of women?. Psychoneuroendocrinology. 2007;32:246–255
  14. Greco T, Graham CA, Bancroft J, Tanner A, Doll HA. The effects of oral contraceptives on androgen levels and their relevance to premenstrual mood and sexual interest: a comparison of two triphasic formulations containing norgestimate and either 35 or 25 microg of ethinyl estradiol. Contraception. 2007;76:8–17
  15. Panzer C, Wise S, Fantini G, et al. Impact of oral contraceptives on sex hormone-binding globulin and androgen levels: a retrospective study in women with sexual dysfunction. J Sex Med. 2006;104–113
  16. Warnock JK, Clayton A, Croft J, Segraves R, Boggs FC. Comparison of androgens in women with hypoactive sexual desire disorder: those on combined oral contraceptives (COCs) vs. those not on COCs. J Sex Med. 2006;3:878–882
  17. Nusbaum MR, Gamble G, Skinner Heiman J. The high prevalence of sexual concerns among women seeking routine gynecological care. J Fam Pract. 2000;49:229–232
  18. Spector IP, Carey MP. Incidence and prevalence of the sexual dysfunctions: a critical review of the empirical literature. Arch Sex Behav. 1990;19:389–408
  19. Ritter P, et al. Internet versus mailed questionnaires: a randomized comparison. J Med Internet Res. 2004;6:e29
  20. Gosling SD, Vazire S, Srivastava S, John OP. Should we trust web-based studies? A comparative analysis of six preconceptions about Internet questionnaires. Am Psychol. 2004;59:93–104

☆ This study was supported by a grant from the Research Foundation of the Department of Obstetrics and Gynaecology, University of Tuebingen, Germany.

☆☆ This study was orally presented at the XXI German Full Professor Conference for OB/GYN (25.-26.09.2009, Innsbruck, Austria).

★ The authors have no conflicts of interest to declare.

PII: S0010-7824(09)00560-5

doi: 10.1016/j.contraception.2009.12.022

Contraception
Volume 82, Issue 2 , Pages 155-159 , August 2010

Article Tools

* Image Usage & Resolution