Contraception
Volume 81, Issue 6 , Pages 510-514 , June 2010

Effect of etonogestrel implant on serum lipids, liver function tests and hemoglobin levels

Received 10 November 2009 ,Revised 9 January 2010 ,Accepted 13 January 2010.

References 

  1. Dorflinger LJ. Metabolic effects of implantable steroid contraceptives for women. Contraception. 2002;65:47–62
  2. Darney P, Patel A, Rosen K, Shapiro LS, Kaunitz AM. Safety and efficacy of a single-rod etonogestrel implant (Implanon): results form 11 international clinical trials. Fertil Steril. 2009;91:1646–1653
  3. Croxatto HB. Progestin implants for female contraception. Contraception. 2002;65:15–19
  4. Meckstroth KR, Darney PD. Implant contraception. Semin Reprod Med. 2001;19:339–354
  5. Bennink HJ. The pharmacokinetics and pharmacodynamics of Implanon, a single-rod etonogestrel contraceptive implant. Eur J Contracept Reprod Health Care. 2000;5(Suppl 2):12–20
  6. Adams K, Beal MW. Implanon: a review of the literature with recommendations for clinical management. J Midwifery Womens Health. 2009;54:142–144
  7. Suherman SK, Affandi B, Korver T. The effects of Implanon on lipid metabolism in comparison with Norplant. Contraception. 1999;60:281–287
  8. Egberg N, van Beek A, Gunnervik C, et al. Effects on the hemostatic system and liver function in relation to Implanon and Norplant. A prospective randomized clinical trial. Contraception. 1998;58:93–98
  9. Warnick GR, Nauck M, Rifai N. Evolution of methods for measurement of HDL-cholesterol: from ultracentrifugation to homogeneous assays. Clin Chem. 2001;47:1579–1596
  10. Clarke R, Emberson JR, Parish S, et al. Cholesterol fractions and apolipoproteins as risk factors for heart disease mortality in older men. Arch Intern Med. 2007;167:1373–1378
  11. Jong Weon Choi . Association between elevated serum hepatic enzyme activity and total body fat in obese humans. Ann Clin Lab Sci. 2003;33:257–264
  12. Stamminger G, Köppel C, Schaub A, et al. Performance of the SE-9000 automated haematology analyser in a laboratory serving a haematological oncology unit. Ann Clin Lab Sci. 2002;20:143–149
  13. Agresti A. Categorical data analysis. 2nd ed. USA: Wiley Interscience; 2002;
  14. Trussell J. Contraceptive efficacy. In:  Hatcher RA,  Trussell J,  Nelson AL,  Cates W,  Stewart F,  Kowal D editor. Contraceptive technology: nineteenth revised edition. New York (NY): Ardent Media; 2007;p. 747–826
  15. Mansour D, Korver T, Marintcheva-Petrova M, Fraser IS. The effects of Implanon on menstrual bleeding patterns. Eur J Contracept Reprod Health Care. 2008;13(Suppl 1):13–28
  16. Yildizbas B, Sahin HG, Kolusari A, Zeteroglu S, Kamacı M. Side effects and acceptability of Implanon®: a pilot study conducted in eastern Turkey. Eur J Contracept Reprod Health Care. 2007;12:248–252
  17. Gezginc K, Balci O, Karatayli R, Colakoglu MC. Contraceptive efficacy and side effects of Implanon. Eur J Contracept Reprod Health Care. 2007;12:362–365
  18. Power J, French R, Cowan F. Subdermal implantable contraceptives versus other forms of reversible contraceptives or other implants as effective methods of preventing pregnancy. Cochrane Database Syst Rev. 2007;18(3):CD001326
  19. Smith A, Reuter S. An assessment of the use of Implanon in three community services. J Fam Plann Reprod Health Care. 2002;28:193–196
  20. Biswas A, Viegas OAC, Roy AC. Effect of Implanon and Norplant subdermal contraceptive implants on serum lipids — a randomized comparative study. Contraception. 2003;68:189–193
  21. Inal MM, Yildirim Y, Ertopcu K, Avci ME, Ozelmas I, Tinar S. Effect of the subdermal contraceptive etonogestrel implant (Implanon®) on biochemical and hormonal parameters (three years follow-up). Eur J Contracept Reprod Health Care. 2008;13:238–242
  22. Merki-Feld GS, Imthurn B, Seifert B. Effects of the progestagen-only contraceptive implant Implanon on cardiovascular risk factors. Clin Endocrinol (Oxf). 2008;68:355–360
  23. Biswas A, Biswas S, Viegas OA. Effect of etonogestrel subdermal contraceptive implant (Implanon) on liver function tests — a randomized comparative study with Norplant implants. Contraception. 2004;70:379–382
  24. Nasr A, Nafeh HM. Effect of etonogestrel contraceptive implant (Implanon®) on portal blood flow and liver functions. Contraception. 2009;79:236–239

PII: S0010-7824(10)00015-6

doi: 10.1016/j.contraception.2010.01.014

Contraception
Volume 81, Issue 6 , Pages 510-514 , June 2010

Article Tools

* Image Usage & Resolution