Contraception
Volume 82, Issue 4 , Pages 373-378 , October 2010

A randomized, double-blind, noninferiority study to compare two regimens of levonorgestrel for emergency contraception in Nigeria

  • Olukayode A. Dada

      Affiliations

    • Centre for Research in Reproductive Health, Olabisi Onabanjo University Teaching Hospital, Sagamu, 121001 Ogun State, Nigeria
    • ,
  • Emily M. Godfrey

      Affiliations

    • Department of Family Medicine and Community Health Sciences, University of Illinois at Chicago, IL 60612, USA
    • Corresponding Author InformationCorresponding author.
    • ,
  • Gilda Piaggio

      Affiliations

    • UNDP/UNFPA/WHO/World Bank Special Programme of Research, Development and Research Training in Human Reproduction, 1211 Geneva 27, Switzerland
    • ,
  • Helena von Hertzen

      Affiliations

    • UNDP/UNFPA/WHO/World Bank Special Programme of Research, Development and Research Training in Human Reproduction, 1211 Geneva 27, Switzerland
    • ,
  • On behalf of the Nigerian Network for Reproductive Health Research and Training

      Affiliations

    • Investigators and study centres of the Nigerian National Network for Reproductive Health Research and Training: Women's Health and Action Research Centre, Benin: F.E. Okonofua, G. Eguzoro; University of Nigeria Teaching Hospital, Enugu: John Okaro, C. Anumba; University College Hospital, Ibadan: Y. Adekunle, Bola Bello; University of Jos Teaching Hospital, Jos: J.A.M. Otubu, N. Izzah; Lagos University Teaching Hospital, Lagos: Bomi Ogedengbe, C. Osifoh; University of Port-Harcourt: Victor Wakwe, K.M. Jonathan; Olabisi Onabanjo University Teaching Hospital, Sagamu: O.L. Odusoga, B. Idowu-Ajiboye, Toyin Aina, K. Oritogun.

Received 17 February 2010 ,Revised 30 May 2010 ,Accepted 2 June 2010.

References 

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  3. Oye-Adeniran BA, Adewole IF, Umoh AV, et al. Sources of contraceptive commodities for users in Nigeria. PLoS Med. 2005;e306:2
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  6. Arowojolu AO, Okewole IA, Adekunle AO. Comparative evaluation of the effectiveness and safety of two regimens of levonorgestrel for emergency contraception in Nigerians. Contraception. 2002;66:269–273
  7. von Hertzen H, Piaggio G, Ding J, et al. Low dose mifepristone and two regimens of levonorgestrel for emergency contraception: a WHO multicentre randomised trial. Lancet. 2002;360:1803–1810
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  9. Glasier AF, Cameron ST, Fine PM, et al. Ulipristal acetate versus levonorgestrel for emergency contraception: a randomised non-inferiority trial and meta-analysis. Lancet. 2010;375:555–562
  10. Population Reference Bureau . 2009 World Population Data Sheet. accessed at http://www.prb.org/Publications/Datasheets/2009/2009wpds.aspxon December 3, 2009
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  13. Abiodun OM, Balogun OR. Sexual activity and contraceptive use among young female students of tertiary educational institutions in Illorin, Nigeria. Contraception. 2009;79:146–149
  14. Abasiattai AM, Umoiyoho AJ, Bassey EA, Etuk SJ, Udoma EJ. Misconception of emergency contraception among tertiary school students in Akwa Ibom State, South-south, Nigeria. Niger J Clin Pract. 2007;10:30–34
  15. Akani C, Enyindah C, Babatunde S. Emergency contraception: knowledge and perception of female undergraduates in the Niger Delta of Nigeria. Ghana Med J. 2008;42:68–70
  16. Obi SN, Ozumba BC. Emergency contraceptive knowledge and practice among unmarried women in Enugu, southeast Nigeria. Niger J Clin Pract. 2008;11:296–299
  17. Ikeme AC, Ezegwui HU, Uzodimma AC. Knowledge, attitude and use of emergency contraception among female undergraduates in Eastern Nigeria. J Obstet Gynaecol. 2005;25:491–493

☆ Clinical Trial Registration: current controlled trials, isrctn.org, ISRCTN69287540.

☆☆ This study was funded by UNDP/UNFPA/WHO/World Bank Special Programme of Research, Development and Research Training in Human Reproduction.

PII: S0010-7824(10)00357-4

doi: 10.1016/j.contraception.2010.06.004

Contraception
Volume 82, Issue 4 , Pages 373-378 , October 2010

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