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Abstract
Effects on metabolic parameters of six subdermal implants of d-norgestrel, norgestrienone
(R2010) and methyl-norgestrienone (R2323) were studied in women. In general, tests
remained within the normal range. An exception was increases in serum transaminase
levels in several subjects on R2323 implants. Average cortisol values showed a tendency
to decrease on all three regimens, but remained within the normal range and the decreases
met tests for statistical significance only with R2323 at six months and R2010 at
12 months. Serum cholesterol levels showed significant decreases on R2010 implants.
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References
- Clinical trial with subdermal implants of methyl-norgestrienone.Contraception. 1977; 16: 155-165
Article info
Publication history
Accepted:
September 1,
1978
Identification
Copyright
© 1978 Published by Elsevier Inc.