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Fertility regulation in nursing women: IV. Long-term influence of a low-dose combined oral contraceptive initiated at day 30 postpartum upon lactation and infant growth

  • H.B. Croxatto
    Affiliations
    Consultorio de Planificación Familiar Centro Nacional de la Familia J.V. Lastarria 29, depto. 101 Chile

    Servicio de Obstetricia y Ginecología Hospital Paula Jaraquemada Santiago, Chile
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  • S. Díaz
    Affiliations
    Consultorio de Planificación Familiar Centro Nacional de la Familia J.V. Lastarria 29, depto. 101 Chile

    Servicio de Obstetricia y Ginecología Hospital Paula Jaraquemada Santiago, Chile
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  • O. Peralta
    Affiliations
    Consultorio de Planificación Familiar Centro Nacional de la Familia J.V. Lastarria 29, depto. 101 Chile

    Servicio de Obstetricia y Ginecología Hospital Paula Jaraquemada Santiago, Chile
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  • G. Juez
    Affiliations
    Consultorio de Planificación Familiar Centro Nacional de la Familia J.V. Lastarria 29, depto. 101 Chile

    Servicio de Obstetricia y Ginecología Hospital Paula Jaraquemada Santiago, Chile
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  • C. Herreros
    Affiliations
    Consultorio de Planificación Familiar Centro Nacional de la Familia J.V. Lastarria 29, depto. 101 Chile

    Servicio de Obstetricia y Ginecología Hospital Paula Jaraquemada Santiago, Chile
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  • M.E. Casado
    Affiliations
    Consultorio de Planificación Familiar Centro Nacional de la Familia J.V. Lastarria 29, depto. 101 Chile

    Servicio de Obstetricia y Ginecología Hospital Paula Jaraquemada Santiago, Chile
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  • A.M. Salvatierra
    Affiliations
    Consultorio de Planificación Familiar Centro Nacional de la Familia J.V. Lastarria 29, depto. 101 Chile

    Servicio de Obstetricia y Ginecología Hospital Paula Jaraquemada Santiago, Chile
    Search for articles by this author
  • P. Miranda
    Affiliations
    Consultorio de Planificación Familiar Centro Nacional de la Familia J.V. Lastarria 29, depto. 101 Chile

    Servicio de Obstetricia y Ginecología Hospital Paula Jaraquemada Santiago, Chile
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  • E. Durán
    Affiliations
    Consultorio de Planificación Familiar Centro Nacional de la Familia J.V. Lastarria 29, depto. 101 Chile

    Servicio de Obstetricia y Ginecología Hospital Paula Jaraquemada Santiago, Chile
    Search for articles by this author
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      Abstract

      The study was designed to test the long-term influence of a low-dose combined oral contraceptive upon lactation and infant growth when treatment was initiated at day 30 postpart um. The contraceptive tested contained ethinyl estradiol 0.03 mg and levonorgestrel 0.15 mg. Two control groups were formed by women who received an injectable placebo or a Copper T at day 30 postpartum. Women in the injectable placebo group received non-hormonal contraceptives at day 90 postpartum. An exacting list of requirements for admission and continuation in the study was applied to all groups.
      The oral contraceptive group had a significantly lower percentage of cases in full nursing from the 4th through the 10th postpartum month when compared to both control groups. The average absolute weight of infants in the oral contraceptive group was significantly lower at several ages when compared to the placebo group but not when compared to the Copper T group. No adverse side effects upon infant's health were detected.
      It was concluded that the oral contraceptive tested showed a moderate inhibitory influence upon lactation when treatment was initiated at the beginning of the second postpartum month.
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