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Abstract
A total of 189 women volunteered to accept subdermal implants for contraception. The
implants were “covered rods”, consisting of a core rod containing equal parts by weight
of levonorgestrel and polydimethylsiloxane and sealed inside a thin-walled tube of
Silastic tubing with medical adhesive. In one study 78 women used 4 3cm rods (study
07) and in the other 111 women used 6 3cm rods. In 5 years of use there were no pregnancies
in either group. Terminations because of menstrual problems were twice as frequent
among the 4-rod users than among users of the 6 rods. Menstrual pattern analysis is
presented for the two rod regimens and compared with the previously reported patterns
for the 6-capsule regimen (NORPLANTR). Long-term
release rates are also presented.

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References
- ICCR Contraception. 1978; 18 (I): 315-333
- Special Issue Studies in Family Planning. 1983; 14: 159-193
- A Five-Year Clinical Trial of Levonorgestrel Silastic Implants (NORPLANT™).Contraception. 1982; 25: 447-456
- Steroid Release from Silastic Capsules and Rods.Contraception. 1978; 18: 367-394
- First year clinical experience with six levonorgestrel rods as subdermal contraception.Contraception. 1979; 20: 167-175
- Clinical and Endocrinological Study of Continuous Levonorgestrel Administration from Subcutaneous Solid Polydimethylsiloxane Rods.Contraception. 1980; 21: 595-615
- Contraception with d-Norgestrel Silastic Rods: Plasma Levels of d-Norgestrel and Influence on the Ovarian Function.Contraception. 1976; 14: 551-562
- Release Rates of Levonorgestrel from SilasticR Capsules. Homogenous Rods and covered Rods in Humans.Contraception. 1983; 27: 483-495
- Life-Table Analysis of IUDs. Problems and Recommendations.Studies in Family Planning. 1977; 8
- Long -Acting Contraceptive Implants, An Analysis of Menstrual Bleeding Patterns.Contraception. 1978; 18: 355-365
Article info
Publication history
Accepted:
March 20,
1985
Received:
February 21,
1985
The International Committee for Contraception Research (ICCR) of the Population CouncilIdentification
Copyright
© 1985 Published by Elsevier Inc.