This paper is only available as a PDF. To read, Please Download here.
In order to investigate possible reasons for inconsistent tubal occlusion when a suspension of quinacrine is introduced into the uterus, the following radiographic investigations were carried out: 4ml of renografin 60 which has the same approximate viscosity as a suspension of quinacrine, were introduced into the uteri of sixteen normal parous women and the distribution followed by fluoroscopy and x-ray. The same type of instrument which had previously been used to introduce quinacrine, namely, a 3.4mm cannula with no cervical occlusive tip, was employed. The contrast material failed to enter one or both oviducts in four out of sixteen cases (25%), even though subsequent hystero-salpingograms revealed patent oviducts. However, if patients wearing IUDs were excluded, renografin 60 failed to enter the patent oviducts in only one out of eleven cases (9%). A much more viscous contrast material, Salpix, failed to enter patent oviducts in one out of thirteen women (8%) including three who were wearing IUDs. There was less peritoneal spillage with the more viscous contrast material. These studies suggest that failure of a suspension of quinacrine to enter the oviduct is at least one reason for failure of this technique to occlude the fallopian tube. They also suggest that a more viscous preparation may lead to more consistent filling of the oviducts when a cannula without an occlusive tip is used to introduce the preparation into the uterus.
To read this article in full you will need to make a payment
Purchase one-time access:Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
One-time access price info
- For academic or personal research use, select 'Academic and Personal'
- For corporate R&D use, select 'Corporate R&D Professionals'
Subscribe:Subscribe to Contraception
Already a print subscriber? Claim online access
Already an online subscriber? Sign in
Register: Create an account
Institutional Access: Sign in to ScienceDirect
- Human Fertility Control by Transvaginal Application of Quinacrine on the Fallopian Tube.Fertil Steril. 1970; 21: 581-589
- Salpix-A New Approach to the Ideal Radiopaque Medium for Hysterosalpingography.Fertil Steril. 1953; 4: 357-370
Tatum, Dr. Howard, Personal Communication.
- Chemically Induced Tubal Occlusion in the Human Female Following a Single Instillation of Quinacrine.Contraception. 1973; 7: 333-339
Accepted: January 29, 1974
☆This work was supported by a grant from the Population Council.
© 1974 Published by Elsevier Inc.