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Abstract
A group of 20 pregnant women requesting therapeutic abortion received a single transcervical
intrauterine instillation of 5 mg prostaglandin F2α in 5 ml of saline between 38 and 46 days after the onset of their last menses. Of
the 20 women, 13 (65%) had a successful termination of pregnancy, while the other
7 patients did not abort. A total of 7 patients, 2 of whom aborted, had severe adverse
reactions, including fever, hemorrhage and hypertension. Three of the 5 women who
did not abort developed septic incomplete abortions. The low incidence of success
and high incidence of complications noted in this study indicate that this method
should not be utilized to terminate early pregnancy.
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References
- The efficacy and acceptability of the “Prostaglandin Impact” in inducing complete abortion during the second week after the missed menstrual period.Prostaglandins. 1973; 3: 125
- Abortifacient activity of intravenously administered prostaglandins.Contraception. 1971; 3: 121
- Termination of early gestation with vaginal prostaglandin F2αtablets.Prostaglandins. 1972; 2: 453
- Therapeutic abortion of early human gestation with vaginal suppositories of prostaglandin F2α.Am. J. Obstet. Gynec. 1973; 117: 795
- Termination of early pregnancy with prostaglandin E2 vaginal suppositories.Contraception. 1973; 8: 255
- Menstrual extraction: Review of 400 procedures at the Women's Services.Contraception. 1973; 8 (New York, New York): 527
Article info
Publication history
Accepted:
February 5,
1974
Identification
Copyright
© 1974 Published by Elsevier Inc.
