Research Article| Volume 9, ISSUE 4, P403-408, April 1974

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Intrauterine administration of prostaglandin F as an outpatient procedure for termination of early pregnancy

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      A group of 20 pregnant women requesting therapeutic abortion received a single transcervical intrauterine instillation of 5 mg prostaglandin F in 5 ml of saline between 38 and 46 days after the onset of their last menses. Of the 20 women, 13 (65%) had a successful termination of pregnancy, while the other 7 patients did not abort. A total of 7 patients, 2 of whom aborted, had severe adverse reactions, including fever, hemorrhage and hypertension. Three of the 5 women who did not abort developed septic incomplete abortions. The low incidence of success and high incidence of complications noted in this study indicate that this method should not be utilized to terminate early pregnancy.
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        • Csapo A.I.
        • Mocsary P.
        • Nagy T.
        • Kaihola H.L.
        The efficacy and acceptability of the “Prostaglandin Impact” in inducing complete abortion during the second week after the missed menstrual period.
        Prostaglandins. 1973; 3: 125
        • Kaufman R.G.
        • Freeman R.K.
        • Mishell Jr., D.R.
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        • Sribyatta B.
        • Mishell Jr., D.R.
        • Ballard C.
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        • Thorneycroft I.H.
        Termination of early gestation with vaginal prostaglandin Ftablets.
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        • Tredway D.R.
        • Mishell Jr., D.R.
        Therapeutic abortion of early human gestation with vaginal suppositories of prostaglandin F.
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        • Tredway D.R.
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