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Research Article| Volume 13, ISSUE 2, P225-230, February 1976

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Screening for autoantibodies in human subjects immunized with Pr-β-HCG-TT

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      Abstract

      Sera from 3 human volunteers immunised with Pr-β-HCG-TT vaccine were tested for possible reactivity with other human tissues. They were found to be negative for antinuclear, antimicrosomal antibodies and rheumatoid factor. The sera from these subjects did not give any reaction with human thyroid, pituitary, parathyroid, adrenal, testes and ovaries as examined by immunofluorescence techniques. They were also devoid of reaction with tissue substrates from baboons, mice and rabbits.
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      References

        • Roitt I.M.
        Essential Immunology.
        Second Edition. Blackwell Scientific Publications, Oxford1974
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        Autoimmunity in pernicious anemia and thyroiditis — A family study.
        Ann. N.Y. Acad. Sci. 1965; 124: 605