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Abstract
13 rhesus monkeys were immunised with the beta-subunit of HCG or its fragments conjugated
with tetanus toxoid or haptens for periods of 3 to 12 months. Of these, 9 monkeys
had been given the tetanus toxoid conjugates. Immediate, Arthus and delayed type of
hypersensitivity skin reactions to intradermal HCG were found to be negative in all
the animals. However, 2 of the hyperimmunized monkeys in which complete Freund's adjuvant
was used, showed delayed hypersensitivity skin reactions when challenged with tetanus
toxoid.
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References
- Gell P.G.H. Coombs R.A. Lachmann P. Clinical aspects of immunology. 3rd ed. Blackwell Scientific Publications, Oxford1974
Article info
Publication history
Accepted:
October 20,
1975
Identification
Copyright
© 1976 Published by Elsevier Inc.
