A randomized trial of the Gyne T 380 and Gyne T 380 slimline intrauterine copper devices

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      To facilitate manufacture and insertion of the Gyne T 380 IUD, design changes were Instituted. Copper collars were seated flush at the ends of the horizontal crossbar of the device. A randomized study of the Gyne T 380 Slimline, the new design, was undertaken in comparison with the standard Gyne T 380. A total of 996 women were enrolled, with 698 Slimline insertions and 298 of the standard Gyne T. No statistically significant difference 1n ease of insertion or in performance was detected between the models. At one year, the pregnancy rate of each model was below 0.5 per 100 and the continuation rate was 79–80 per 100. Pelvic inflammatory disease or endometritis was found in one percent of subjects in the first year. This is the seventh multicenter randomized study of a collared T IUD with 380 mm2 of copper surface. In all seven, the one-year gross pregnancy rate has been 1.2 per 100 or lower.
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        • Sivin I.
        • Stern J.
        Long-acting, more effective Copper T IUDs, A summary of U.S. experience, 1970–1975.
        Stud. Fam. Plann. 1979; 10: 263-281
        • Jain A.K.
        • Sivin I.
        Life-table analysis of IUDs: Problems and recommendations.
        Stud. Fam. Plann. 1977; 8: 25-47
        • Heartwell S.F.
        • Schlesselman S.
        Risk of uterine perforation among users of intrauterine devices.
        Obstet. Gynecol. 1983; 61: 31
        • Sivin I.
        The intrauterine device and uterine perforation. Obstet.
        Gynecol. 1984; 64: 744
        • World Health Organization
        Special Programme of Research, Development and Research Training in Human Reproduction.
        in: 6th Edition. Intrauterlne devices, 13th Annual Report. 1984: 52-57
        • Cole L.P.
        • Potts D.M.
        • Aranda C.
        • Behlilovic B.
        • Etman E.-S.
        • Moreno J.
        • Randic L.
        An evaluation of the TCu 380Ag and the Multiload Cu375.
        Fertil. Steril. 1985; 43: 214-217
        • Sivin I.
        • Stern J.
        • Diaz J.
        • Diaz M.M.
        • Faundes A.
        • El Mahgoub S.
        • Diaz S.
        • Pavez M.
        • Coutinho E.
        • Mattos C.E.R.
        • McCarthy T.
        • Mishell Jr., D.R.
        • Shoupe D.
        • Alvarez F.
        • Brache V.
        • Jiminez E.
        Two years of intrauterine contraception with levonorgestrel and with copper: A randomized comparison of the TCu 380Ag and levonorgestrel 20 mcg/day devices.
        Contraception. 1987; 35: 245-255
        • Indian Council Of Medical Research
        • Task Force on IUD
        Randomized clinical trial with intrauterine devices (levonorgestrel intrauterine device (LNg), Cu 7, 380Ag, CuT 220G, CuT 200B). A 36-month study.
        Contraception. 1989; 39: 37-52
        • Sung S.
        • Qian L.-j.
        • Liu X.
        Comparative clinical experience with 3 lUDs, TCu 380Ag, TCu 220C, and Mahua ring, in Tianjin, People's Republic of China.
        Contraception. 1984; 29: 229-239
        • Champion C.B.
        • Behlilovic B.
        • Arosemana J.M.
        • Randic L.
        • Cole L.P.
        • Wilkens L.P.
        A three-year evaluation of the TCu 380Ag and Multiload Cu375 intrauterine devices.
        Contraception. 1988; 38: 631-639