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Abstract
A case-control study on different groups of isolated congenital limb deficiency was
performed in a ten-year population-based and revised Hungarian data set. A higher
rate of one contraceptive pill type with relatively high dose (ethynodiol diacetate
1.0 mg + ethinyloestradiol 0.05 mg) used in the periconceptional period was found
in the mothers of cases with terminal transverse defect (adjusted relative odds 1.9
with 95% confidence interval of 1.1–3.4). This risk is minimised by the use of recent
low-dose pills.
Keywords
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Article info
Publication history
Accepted:
August 24,
1994
Received in revised form:
July 11,
1994
Received:
April 5,
1994
Identification
Copyright
© 1995 Published by Elsevier Inc.