Abstract
This 1-year randomized study was carried out at family-planning clinics of two university
hospitals to compare the safety and acceptability of a levonorgestrel-releasing intrauterine
system (LNG IUS) and oral contraceptives (OCs) in young nulliparous women. The study
population consisted of 200 women aged 18–25 years seeking contraception. Ninety-four
women entered the LNG IUS group and 99 entered the OC group. Continuation rates, reasons
leading to discontinuation, adverse events, menstrual questionnaires, subjective well-being
and sexual behavior were evaluated. Nineteen women (20%) in the LNG IUS group discontinued
the study during the 1-year observation period, and 27 discontinued (27%) in the OC
group. The most common reason (31%) for discontinuation in the IUS group was pain.
In the OC group, hormonal side effects were the predominant medical reason for study
termination. The safety and acceptability of the LNG IUS for contraception was observed
to be as good as with OCs, with a high continuation rate.
Keywords
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Article info
Publication history
Accepted:
November 17,
2003
Received in revised form:
October 30,
2003
Received:
May 29,
2003
Identification
Copyright
© 2004 Elsevier Inc. Published by Elsevier Inc. All rights reserved.
