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Original research article| Volume 72, ISSUE 1, P14-18, July 2005

The acceptability of self-administration of subcutaneous Depo-Provera

  • Fatim Lakha
    Correspondence
    Corresponding author. Contraceptive Development Network, Centre for Reproductive Biology, University of Edinburgh, Edinburgh, EH16 4BS Scotland, UK. Tel.: +44 1212426360; fax: +44 1316216363.
    Affiliations
    NHS Lothian Primary and Community Division, Family Planning and Well Woman Services, Edinburgh, EH4 1NL Scotland, UK

    Contraceptive Development Network, Centre for Reproductive Biology, University of Edinburgh, Edinburgh, EH16 4BS Scotland, UK
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  • Charlotte Henderson
    Affiliations
    NHS Lothian Primary and Community Division, Family Planning and Well Woman Services, Edinburgh, EH4 1NL Scotland, UK
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  • Author Footnotes
    1 The author is a member of the International Advisory Board to Pfizer for DMPA-SC.
    Anna Glasier
    Footnotes
    1 The author is a member of the International Advisory Board to Pfizer for DMPA-SC.
    Affiliations
    NHS Lothian Primary and Community Division, Family Planning and Well Woman Services, Edinburgh, EH4 1NL Scotland, UK

    Contraceptive Development Network, Centre for Reproductive Biology, University of Edinburgh, Edinburgh, EH16 4BS Scotland, UK
    Search for articles by this author
  • Author Footnotes
    1 The author is a member of the International Advisory Board to Pfizer for DMPA-SC.

      Abstract

      Depo-Provera (depot medroxyprogesterone acetate, or DMPA) is an important contraceptive option for women worldwide. Currently, it is only available in intramuscular form requiring regular quarterly routine attendance at a health facility. A new subcutaneous preparation has been developed. This is self-administrable and could potentially reduce need for routine attendance to an annual visit.
      In a questionnaire survey of 176 women currently using DMPA, 67% would prefer to self-administer. Of the 33% who did not wish to self-administer, the most common reasons were a fear of needles (62%) and concern regarding incorrect administration (43%). In a second survey of 313 women not currently using DMPA, 64% of women said they would prefer to attend less often for contraceptive supplies. Twenty-six percent of women who had never used DMPA and 40% of ex-users would seriously consider DMPA if self-administration were possible.
      Our findings would suggest that the advent of subcutaneous self-administrable Depo-Provera with appropriate training and reminder system is likely to be beneficial and popular with many women.

      Keywords

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      References

      1. Population Reports. New era for injectables. 1995, volume XXIII, number 2. Series K, No 5.

      2. Piccinino LJ, Mosher WD. Trends in contraceptive use in the United States: 1982���1995. Fam Plann Perspect 1998;30:4���10, 46.

      3. Dawe F. Meltzer H. Contraception and sexual health. Office for National Statistics, London2002 (Available at:)
        • World Health Organization
        Selected practice recommendations for contraceptive use.
        WHO, Geneva2002 (Available at:)
        • Jain J.
        • Dutton C.
        • Nicosia A.
        • Wajszczuk C.
        • Bode F.R.
        • Mishell D.R.
        Pharmacokinetics, ovulation suppression and return to ovulation following a lower dose subcutaneous formulation of Depo Provera.
        Contraception. 2004; 70: 11-18
        • Henshaw S.K.
        Unintended pregnancy in the United States.
        Fam. Plann. Perspect. 1998; 30: 24-29
        • Bahamondes L.
        • Marchi N.M.
        • Nakagava H.M.
        • et al.
        Self-administration with Uniject�� of the once-a-month injectable contraceptive Cyclofem.
        Contraception. 1997; 56: 301-304
        • Keder L.M.
        • Rulin M.C.
        • Gruss J.
        Compliance with depot medroxyprogesterone acetate: a randomized controlled trial of intensive reminders.
        Am. J. Obstet. Gynecol. 1995; 169: 583-585