Abstract
Objective
Copper T380A is one of the most commonly prescribed intrauterine devices (IUDs). However,
there are few reports of its systemic health effects. This study evaluates the association
between the use of T380A IUD and blood Cu levels in a group of Mexican users.
Methods
Eighty-six T380A users and eight nonusers were recruited. Blood Cu levels were measured
using an atomic absorption spectrophotometic technique.
Results
In IUD users, mean blood Cu level was significantly higher than in nonusers, 216.63
vs. 107.47 ��g/dL (p���.001), and above the normal blood Cu level range of 80���160
��g/dL. No significant difference in blood Cu levels was observed by age or length
of time of IUD use.
Conclusions
The observed higher blood Cu levels among T380A user stands out in sharp contrast
to previous reports of other types of Cu IUDs. Further research should evaluate if
the observed levels are associated to toxic effects with the general population or
special groups.
Keywords
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Article info
Publication history
Published online: June 09, 2005
Accepted:
February 17,
2005
Received in revised form:
February 15,
2005
Received:
November 23,
2004
Identification
Copyright
© 2005 Elsevier Inc. Published by Elsevier Inc. All rights reserved.
