Abstract
Objectives
The study was conducted to determine whether placenta previa increases bleeding during
gemeprost-induced termination of second-trimester pregnancy.
Methods
We carried out a retrospective study of 158 second-trimester terminations between
12 and 21 weeks' gestation. We compared the intraoperative blood loss among three
groups: women without placenta previa undergoing gemeprost termination, women with
placenta previa undergoing gemeprost termination and women with placenta previa undergoing
dilatation and evacuation (D&E).
Results
Eleven of 158 women (7.0%) had placenta previa; four underwent D&E and seven had gemeprost
termination. There was no statistical difference in mean intraoperative blood loss
among the three groups, although one of the seven women with placenta previa who underwent
gemeprost termination developed serious bleeding requiring blood transfusion.
Conclusion
The use of gemeprost for second-trimester pregnancy termination in women with placenta
previa seems to be relatively safe and does not increase intraoperative blood loss
in the majority of cases.
Keywords
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References
- Williams obstetrics.22nd ed. McGraw-Hill, New York2005
- The epidemiology of placenta previa in the United States, 1979 through 1987.Am J Obstet Gynecol. 1993; 168: 1424-1429
- Natural history of placenta previa ascertained by diagnostic ultrasound.Am J Obstet. 1979; 133: 287-291
- Persistence of placenta previa according to gestational age at ultrasound detection.Obstet Gynecol. 2002; 99: 692-697
- The effect of placenta previa on blood loss in second-trimester pregnancy termination.Obstet Gynecol. 1994; 84: 58-60
- Late midtrimester pregnancy termination in the presence of placenta previa.J Reprod Med. 2003; 48: 175-178
- A clinician's guide to medical and surgical abortion.Churchill Livingstone, Philadelphia1999
- Misoprostol and pregnancy.N Engl J Med. 2001; 344: 38-47
- A retrospective study of 932 second trimester terminations using gemeprost (16,16-dimethyl-trans delta2 PGE1 methyl ester).Prostaglandins. 1992; 44: 65-74
- Second- and third-trimester therapeutic terminations of pregnancy in cases with complete placenta previa ��� does feticide decrease postdelivery maternal hemorrhage?.Fetal Diagn Ther. 2004; 19: 475-478
Article info
Publication history
Published online: January 17, 2007
Accepted:
November 2,
2006
Received in revised form:
November 2,
2006
Received:
March 22,
2006
Identification
Copyright
© 2007 Elsevier Inc. Published by Elsevier Inc. All rights reserved.
