Abstract
Purpose
The risk of 12 types of cancer in relation to use of monthly injectable contraceptives
was assessed in a prospective study in Shanghai, China.
Methods
From 1989 to 1991, an in-person interview was administered to 267,400 female textile
workers to ascertain information on risk factors for breast cancer, contraceptive
use and induced abortions. The cohort was followed until July 2000 for incident cancer
cases. Cox proportional hazards analysis was used to calculate incidence rate ratios
for specific types of cancer in women who ever had used monthly injectable contraceptives
and by length of use.
Results
There was a reduced risk of uterine corpus cancer for women who had ever used monthly
injectable contraceptives. No association was observed between the use of monthly
injectable contraceptives and the risk of all cancers combined and for any of the
11 other cancersconsidered.
Conclusion
There appears to be no evidence of an increased risk of cancer after exposure to monthly
injectable contraceptives in our study.
Keywords
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Article info
Publication history
Published online: May 21, 2007
Accepted:
March 15,
2007
Received in revised form:
February 28,
2007
Received:
November 30,
2006
Identification
Copyright
© 2007 Elsevier Inc. Published by Elsevier Inc. All rights reserved.
