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Original research article| Volume 76, ISSUE 1, P18-22, July 2007

How do health care professionals respond to advice on adverse side effects of contraceptive methods? The case of Depo Provera��

  • Anna Glasier
    Correspondence
    Corresponding author. Family Planning & Well Woman Services, Edinburgh, EH4 1NL Scotland, UK. Tel.: +44 1313154874; fax: +44 1313322931.
    Affiliations
    London School of Hygiene and Tropical Medicine, University of Edinburgh, Edinburgh, E816 4SB Scotland, UK

    Centre for Sexual and Reproductive Health Research, University of Edinburgh, Edinburgh, E816 4SB Scotland, UK
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  • Yan Yan
    Affiliations
    London School of Hygiene and Tropical Medicine, University of Edinburgh, Edinburgh, E816 4SB Scotland, UK
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  • Kaye Wellings
    Affiliations
    London School of Hygiene and Tropical Medicine, University of Edinburgh, Edinburgh, E816 4SB Scotland, UK
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      Abstract

      Context

      Depomedroxyprogesterone acetate (DMPA) (Depo Provera��) is a long-acting contraceptive popular in the United Kingdom, particularly among young women. In the United States, use of DMPA has been instrumental in reducing teenage pregnancy rates. Evidence for a detrimental effect of DMPA on bone mineral density led to advice from drug regulatory authorities in the United Kingdom and the United States, recommending caution in prescribing DMPA, particularly for young people.

      Objective

      The study was conducted to explore changes in practice in response to prescribing advice about DMPA among primary care doctors and nurses working in the UK.

      Methods

      A self-completed questionnaire sent to 420 primary care health professionals.

      Results

      In response to the advice, 16% of practitioners would deter all women, and one third would deter young women, from using DMPA.One in five practitioners would limit use of DMPA to 2 years. Fewer than one in 10 would suggest contraceptive implants as an alternative contraceptive.

      Conclusions

      The response of primary care professionals in their prescribing advice about DMPA risks increasing rates of unintended pregnancy in the UK, particularly among teenagers. The findings demonstrate an urgent need for a clear, balanced approach to advising health professionals on how to respond to new findings about adverse effects of contraceptives.

      Keywords

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      References

        • Shickle D.
        On a supposed right to lie [to the public] from benevolent motives: communicating health risks to the public.
        Med Health Care Philos. 2000; 3: 241-249
        • Furedi A.
        The public health implications of the 1995 ���pill scare���.
        Hum Reprod Update. 1999; 5: 621-626
        • Wood R.
        • Botting B.
        • Dunnell K.
        Trends in conceptions before and after the 1995 pill scare.
        Popul Trends. 1997; 89: 5-12
        • Bromham D.R.
        Another pill scare ��� should we audit its impact?.
        Audit Unit News. 1996; 1: 2-3
        • Flett G.
        • Gurney E.
        • McKessock L.
        • Reid J.
        Impact of the October 1995 pill scare in Grampian.
        Br J Fam Plann. 1998; 24: 18-20
        • de Vries C.S.
        • van den Berg P.B.
        • de Jong-van den Berg L.T.
        Oral contraceptive use before and after the latest pill scare in The Netherlands. Changes in oral contraceptive use and how users change.
        Contraception. 1998; 57: 247-249
        • Skjeldestad F.E.
        Increased number of induced abortions in Norway after media coverage of adverse vascular events from the use of third-generation oral contraceptives.
        Contraception. 1997; 55: 11-14
        • Taylor T.
        • Keyse L.
        • Bryant A.
        Contraception and sexual health 2005/06. A report on research using the ONS Omnibus Survey produced by the Office for National Statistics on behalf of the Department of Health, London.
        Office for National Statistics, London2006
        • Scholes D.
        • LaCroix A.Z.
        • Ichikawa L.E.
        • Barlow W.E.
        • Ott S.M.
        Injectable hormone contraception and bone density: results from a prospective study.
        Epidemiology. 2002; 13: 581-587
        • Berenson A.B.
        • Radecki C.M.
        • Grady J.J.
        • Rickert V.I.
        • Thomas A.
        Effects of hormonal contraception on bone mineral density after 24 months of use.
        Obstet Gynecol. 2004; 103: 899-906
        • Petitti D.B.
        • Piaggio G.
        • Mehta S.
        • Cravioto M.C.
        • Meirik O.
        • for the WHO study of hormonal contraception and bone health
        Steroid hormone contraception and bone mineral density: a cross-sectional study in an international population.
        Obstet Gynecol. 2000; 95: 736-744
      1. Updated prescribing advice on the effect of Depo-Provera contraception on bones.
        (16Nov2004 [Accessed November 29, 2006])
        • Busen N.H.
        • Britt R.B.
        • Rianon N.
        Bone mineral density in a cohort of adolescent women using depot medroxyprogesterone acetate for one to two years.
        J Adolesc Health. 2003; 32: 257-259
        • Kaunitz A.M.
        Long-acting hormonal contraceptives ��� indispensable in preventing pregnancy.
        J Adolesc Health. 2007; 97: 1-3
        • Teenage pregnancy
        Social Exclusion Unit. London; 1999.
        (Available at:) ([Accessed May 3, 2007])
      2. Scottish Executive. Respect & responsibility ��� strategy and action plan for improving sexual health. Edinburgh, 2005.
        (Available at:) ([Accessed May 3, 2007])
        • Santelli J.S.
        • Lindberg L.D.
        • Finer L.B.
        • Singh S.
        Explaining recent declines in adolescent pregnancy in the United States: the contribution of abstinence and improved contraceptive use.
        Am J Public Health. 2007; 97: 1-7
      3. National Institute for Health and Clinical Excellence long-acting reversible contraception.
        (Accessed 11/25/06)
        • Westhoff C.
        Contraceptive adherence and continuation rates.
        in: Glasier A. Wellings K. Critchley H. Contraception and contraceptive use. RCOG Press, London (UK)2005: 108-118
        • Darney P.D.
        • Callegari L.S.
        • Swift A.
        • Atkinson E.S.
        • Robert A.M.
        Condom practices of urban teens using Norplant contraceptive implants, oral contraceptives and condoms for contraception.
        Am J Obstet Gynecol. 1998; 180: 929-937
        • Stevens-Simon C.
        • Kelly L.
        • Kulick R.
        A village would be nice but��� ���it takes a long-acting contraceptive to prevent repeat adolescent pregnancies.
        Am J Prev Med. 2001; 21: 60-65
        • Rickert V.I.
        • Tiezzi L.
        • Lipschutz J.
        • Leon J.
        • Vaughan R.D.
        • Westhoff C.
        Depo now: preventing unintended pregnancies among adolescents and young adults.
        J Adolescent Health. 2007; 97: 22-28
      4. Wellings K. Zhihing Z. Barrett G. Krentel A. Glasier A. Attitudes towards long acting methods of contraception in general practice in the UK. Contraception [submitted].

      5. World Health Organisation. Technical consultation on the effect ofhormonal contraception on bone health. Summary Report 2006. http://www.who.int/reproductive-health/family_planning/docs/hc_bonehealth/consultation_rpt.pdf [Accessed March 9, 2007].

        • Grady W.R.
        • Bill J.O.G.
        • Klepinger D.H.
        Contraceptive method switching in the United States.
        Perspect Sex Reprod Health. 2002; 34: 135-145
        • Lakha F.
        • Glasier A.
        Continuation rates of Implanon in the UK: data from an observational study in a clinical setting.
        Contraception. 2006; 74: 287-289
        • Little P.
        • Griffin S.
        • Kelly J.
        • Dickson N.
        • Sadler C.
        Effect of educational leaflets and questions on knowledge of contraception in women taking the combined contraceptive pill: randomised controlled trial.
        BMJ. 1998; 316: 1948-1952
        • Berry D.C.
        • Raynor D.K.
        • Knapp P.
        • Bersellini E.
        Official warnings on thromboembolism risk with oral contraceptives fail to inform users adequately.
        Contraception. 2002; 66: 305-307
        • Smith L.F.
        • Whitfield M.J.
        Women's knowledge of taking oral contraceptive pills correctly and of emergency contraception: effect of providing information leaflets in general practice.
        Br J Gen Pract. 1995; 45: 409-414