Abstract
Background
Subcutaneous depo-medroxyprogesterone acetate (DMPA-SC) offers the possibility of
self-administration.
Study Design
This is a pilot study of self-administration of DMPA-SC. Existing users of the intramuscular
preparation (DMPA-IM) who wished to self-inject (n=64) were taught self-administration using DMPA-SC. The main outcome was the continuation
rate of the method at 12 months compared to a control group of existing users of DMPA-IM
(n=64) who continued to attend a clinic to receive the method. Women's satisfaction
with the method and the proportion of self-injections given at correct time were also
determined.
Results
The 12-month discontinuation rate of the DMPA-SC group (12%) did not differ significantly
from that of the DMPA-IM group (22%) (95% confidence intervals of 13%���33% and 6%���23%
for DMPA-SC and DMPA-IM, respectively; p=.23). All self-injections were given within
the appropriate interval. There was no significant difference in the proportion of
women in either group who were satisfied with the method.
Conclusion
Self-administration of DMPA-SC for contraception is feasible and is associated with
similar continuation rates and satisfaction to clinician-administered DMPA-IM.
Keywords
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Article info
Publication history
Published online: November 14, 2011
Accepted:
October 5,
2011
Received in revised form:
September 15,
2011
Received:
June 11,
2011
Footnotes
���Funding: This project was funded by an independent research grant from Sayana, Pfizer Inc., USA.
������Competing interests: There are no competing interests.
Identification
Copyright
© 2012 Elsevier Inc. Published by Elsevier Inc. All rights reserved.
