Intramuscular depot medroxyprogesterone acetate (DMPA-IM) is now available in subcutaneous (SC) formulation, potentially allowing for home-based self-administration. We examined adolescents’ interest in and proficiency at DMPA-SC self-administration.
This is a planned secondary analysis of a randomized controlled trial comparing pain between DMPA-IM and DMPA-SC. In the trial, study participants (N=55) aged 14–21 years were recruited at DMPA initiation and randomized to receive DMPA-IM or DMPA-SC. Participants received the alternate formulation at 3 months, chose formulation at 6 months and could learn self-administration at 9 months. The current analysis is of the women who chose self-administration of DMPA-SC. Proficiency was rated for each step of self-administration: independently [I], with reassurance [R], with verbal instruction [V] or nurse performed [RN]. Data were analyzed using descriptive and comparative statistics.
Thirty-five percent (19/55) of participants learned self-administration. Proficiency ratings were as follows: chose injection site (I=78.9%, R=5.3%, V=5.3%, RN=10.5%), cleaned site (I=89.5%, RN=10.5%), assembled injection device (I=47.4%, R=36.8%, V=15.8%), self-injected (I=31.6%, R=36.8%, V=15.8%, RN=15.8%) and disposed of device (I=21.1%, R=21.1%, RN=57.9%).
Many adolescents are interested in and capable of DMPA-SC self-administration with brief education and minimal assistance.
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Published online: January 07, 2013
Accepted: November 26, 2012
Received in revised form: November 24, 2012
Received: August 29, 2011
☆Disclosure: None of the authors have a conflict of interest.
☆☆Sources of financial support: HRSA/T71 MC00008 and NIH/NCRR RR025761.
© 2013 Elsevier Inc. Published by Elsevier Inc. All rights reserved.