Abstract
Objective
Postpartum contraception is critical in women with gestational diabetes mellitus (GDM).
We evaluated the effect of the levonorgestrel intrauterine system (LNG-IUS) on glucose
tolerance in postpartum women with GDM.
Study design
The study is a descriptive analysis of 12-month glucose tolerance in women with recent
GDM who used the LNG-IUS, the copper IUD or postpartum sterilization.
Results
Twelve months postpartum, 3 of 13 LNG-IUS users (23.1%) and 1 of 6 nonhormonal contraceptive
users (16.6%) had prediabetes. No woman developed overt diabetes.
Conclusions
This study is the first and only to measure the metabolic effects of the LNG-IUS women
with GDM. Larger trials are necessary.
Implications
Use of levonorgestrel intrauterine contraception does not appear to negatively affect
glucose tolerance in postpartum women with a history of gestational diabetes. Additional
appropriately powered clinical studies are needed to confirm these results.
Keywords
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Article info
Publication history
Published online: August 11, 2014
Accepted:
August 6,
2014
Received in revised form:
August 4,
2014
Received:
July 9,
2014
Footnotes
☆Funded by the Society of Family Planning.
Identification
Copyright
© 2014 Elsevier Inc. Published by Elsevier Inc. All rights reserved.
