Postpartum contraception is critical in women with gestational diabetes mellitus (GDM). We evaluated the effect of the levonorgestrel intrauterine system (LNG-IUS) on glucose tolerance in postpartum women with GDM.
The study is a descriptive analysis of 12-month glucose tolerance in women with recent GDM who used the LNG-IUS, the copper IUD or postpartum sterilization.
Twelve months postpartum, 3 of 13 LNG-IUS users (23.1%) and 1 of 6 nonhormonal contraceptive users (16.6%) had prediabetes. No woman developed overt diabetes.
This study is the first and only to measure the metabolic effects of the LNG-IUS women with GDM. Larger trials are necessary.
Use of levonorgestrel intrauterine contraception does not appear to negatively affect glucose tolerance in postpartum women with a history of gestational diabetes. Additional appropriately powered clinical studies are needed to confirm these results.
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Published online: August 11, 2014
Accepted: August 6, 2014
Received in revised form: August 4, 2014
Received: July 9, 2014
☆Funded by the Society of Family Planning.
© 2014 Elsevier Inc. Published by Elsevier Inc. All rights reserved.