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☆Clinical trial registration number: NCT00884260.
☆☆Conflicts of interest:
☆☆Dr. Guangsheng Fan has provided expert opinion for Bayer HealthCare and Merck Sharp & Dohme and has been supported to present at, and attend, conferences by Bayer HealthCare. Dr. Fan's institution received grants from Bayer HealthCare for conducting this phase III clinical trial of LNG-IUS 8.
☆☆Dr. Sukho Kang has provided expert opinion for Bayer HealthCare.
☆☆Prof. Mulan Ren has provided expert opinion for AstraZeneca, Bayer HealthCare, Merck Serono, Merck Sharp & Dohme and Takeda and has been supported to present at, and attend, conferences by Bayer HealthCare.
☆☆Dr. Edith Weisberg has provided expert opinion for Bayer HealthCare and Merck Sharp & Dohme, has been supported to attend conferences by Bayer HealthCare and has obtained research funding for investigator-initiated research from both companies.
☆☆Dr. Eeva Lukkari-Lax is an employee of Bayer Oy, Finland.
☆☆Dr. Katrin Roth is an employee of Bayer Pharma AG, Berlin, Germany.
☆☆Dr. SoYoung Shin is an employee of Bayer HealthCare Pharmaceuticals, Seoul, Republic of Korea.