Abstract
Objective
To describe treatment and outcomes of patients with confirmed cesarean scar ectopic
pregnancy (CSEP) at a tertiary referral center.
Study Design
We reviewed a de-identified family planning clinical database for patients seen by
our subspecialty service for CSEP from January 2017 through December 2021 in this
case series. We extracted referral information, final diagnosis, management, and outcome
measures including estimated blood loss (EBL), secondary procedures and treatment
complications.
Results
Of 57 cases referred for suspected CSEPs, 23 (40%) had confirmed diagnoses; one additional
case was diagnosed during clinic evaluation for early pregnancy loss. Most (n=50 [88%])
referrals occurred in the last 2 years of the 5-year study period. Of 24 confirmed
CSEP cases, 8 were pregnancy losses at the time of diagnosis. Fourteen cases were
≤50 days gestation or gestational size (7 [50%] pregnancy losses) and 10 >50 days
gestation (range 39-66 days). We treated all 14 patients ≤50 days primarily with suction
aspiration under ultrasound guidance in an operating room with no complications and
EBL of 14±10 mL. Of the ten patients >50 days (maximum 66 days), 7 were managed with
primary aspiration of which 5 were uncomplicated. We treated one patient (57 days)
had primary intrauterine double-catheter balloon with immediate hemorrhage requiring
uterine artery embolization followed by an uncomplicated suction aspiration.
Conclusion
Patients with confirmed CSEPs at 50 days or less gestation or gestational size can
likely be primarily treated with suction aspiration with low risk for significant
adverse outcomes. Treatment success and complications are directly related to gestational
age at treatment.
Keywords
To read this article in full you will need to make a payment
Purchase one-time access:
Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online accessOne-time access price info
- For academic or personal research use, select 'Academic and Personal'
- For corporate R&D use, select 'Corporate R&D Professionals'
Subscribe:
Subscribe to ContraceptionAlready a print subscriber? Claim online access
Already an online subscriber? Sign in
Register: Create an account
Institutional Access: Sign in to ScienceDirect
References
- Society for Maternal-Fetal Medicine Consult Series #63: Cesarean scar ectopic pregnancy.Am J Obstet Gynecol. 2022; 227: B9-B20https://doi.org/10.1016/j.ajog.2022.06.024
- Cesarean Scar Pregnancy: Diagnosis and Pathogenesis.Obstet Gynecol Clin North Am. 2019; 46: 797-811https://doi.org/10.1016/j.ogc.2019.07.009
- Cesarean Scar Pregnancy: A Systematic Review.J Minim Invasive Gynecol. 2017; 24: 731-738https://doi.org/10.1016/j.jmig.2017.02.020
- Caesarean scar ectopic pregnancy: diagnostic challenges and management options.The Obstetrician & Gynaecologist. 2017; 19: 13-20https://doi.org/10.1111/tog.12355
- Outcome of Cesarean scar pregnancy managed expectantly: systematic review and meta-analysis.Ultrasound Obstet Gynecol. 2018; 51: 169-175https://doi.org/10.1002/uog.17568
- Natural history of early first-trimester pregnancies implanted in Cesarean scars.Ultrasound Obstet Gynecol. 2015; 46: 367-375https://doi.org/10.1002/uog.14775
- Cesarean Scar Pregnancies: A Systematic Review of Treatment Options.J Minim Invasive Gynecol. 2017; 24: 915-925https://doi.org/10.1016/j.jmig.2017.05.019
- A new minimally invasive treatment for cesarean scar pregnancy and cervical pregnancy.Am J Obstet Gynecol. 2016; 215 (e1-8): 351https://doi.org/10.1016/j.ajog.2016.03.010
- Foley balloon catheter to prevent or manage bleeding during treatment for cervical and Cesarean scar pregnancy.Ultrasound Obstet Gynecol. 2015; 46: 118-123https://doi.org/10.1002/uog.14708
- Maternal morbidity after double balloon catheter management of cesarean scar and cervical pregnancies.Obstet Gynecol. 2022; 140: 933-935https://doi.org/10.1097/AOG.0000000000004977
- The PROCESS 2020 Guideline: Updating Consensus Preferred Reporting Of CasESeries in Surgery (PROCESS) Guidelines.Int J Surg. 2020; 84 (PROCESS Group): 231-235https://doi.org/10.1016/j.ijsu.2020.11.005
- Factors associated with successful transabdominal sonography-guided dilation and curettage for early cesarean scar pregnancy.Int J Gynaecol Obstet. 2015; 131: 281-284https://doi.org/10.1016/j.ijgo.2015.06.029
Article info
Publication history
Accepted:
March 13,
2023
Received in revised form:
March 4,
2023
Received:
December 6,
2022
Publication stage
In Press Accepted ManuscriptFootnotes
☆Presented in part as a poster at the American College of Obstetricians and Gynecologists’ Annual Clinical and Scientific Meeting, May 6-8, 2022, San Diego, CA.
Identification
Copyright
© 2023 Elsevier Inc. All rights reserved.