Advertisement

Postcoital contraceptive activity of some indigenous plants in rats

      Abstract

      Crude ethanolic extract of seeds of Cichorium intybus and aerial parts of Guetterda andamanica, Memcylon lushingtonii, and Solanum crassypetalum and their fractions were evaluated for postcoital contraceptive efficacy in adult female Sprague-Dawley rats. The extracts were administered orally in days 1–10 postcoitum, and significant contraceptive activity was observed. On fractionation, the activity was localized primarily in the chloroform- or butanol-insoluble fractions. The activity in these fractions was invariably associated with a significantly reduced number of implantations.

      Keywords

      To read this article in full you will need to make a payment

      Purchase one-time access:

      Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
      One-time access price info
      • For academic or personal research use, select 'Academic and Personal'
      • For corporate R&D use, select 'Corporate R&D Professionals'

      Subscribe:

      Subscribe to Contraception
      Already a print subscriber? Claim online access
      Already an online subscriber? Sign in
      Institutional Access: Sign in to ScienceDirect

      References

        • Chopra R.N.
        • Nayar S.L.
        • Chopra I.C.
        Glossary of Indian Medicinal Plants. CSIR, New Delhi1956: 64
        • Casey R.C.D.
        Alleged antifertility plants of India.
        Indian J Med Sci. 1960; 14: 590-600
        • Kamboj V.P.
        A review of Indian medicinal plants with interceptive activity.
        Indian J Med Res. 1988; 87: 336-355
        • Singh M.M.
        • Agnihotri A.
        • Garg S.N.
        • et al.
        Antifertility and hormonal properties of certain carotene sesquiterpenes of Ferula jaeschkeana.
        Planta Medica. 1988; 6: 492-494
      1. Taskforce on Indigenous Plants for Fertility Regulation (1982) MB-30/MB-31. A method for examining the effect of plant extracts administered orally/subcutaneously during the first 10 days of pregnancy in the rat. The World Health Organisation.

        • Prakash A.O.
        • Mathur R.
        Screening of Indian plants for antifertility activity.
        Indian J Exp Biol. 1976; 14: 623-626
        • Prakash A.O.
        Evaluation biologique de l’efficacité de l’action contraceptive d’extraits de certaines plantes medicinales chez la femme.
        Contracept Fertil Sex. 1985; 13: 649-655