Abstract
The effect of an ethanolic extract (200 mg/kg/day, intraperitoneally, for 20 days)
and a hydroalcoholic extract (300 mg/kg/day, orally, for 30 days) of Achillea millefolium L. (yarrow) flowers on the spermatogenesis of Swiss mice was studied by evaluating
morphologic characteristics with the light and electron microscopes. The alterations
observed were exfoliation of immature germ cells, germ cell necrosis, and seminiferous
tubule vacuolization. Animals treated with the extracts had an increased number of
metaphases in the germ epithelium that might be due to cytotoxic substances or substances
stimulating cell proliferation.
Keywords
To read this article in full you will need to make a payment
Purchase one-time access:
Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online accessOne-time access price info
- For academic or personal research use, select 'Academic and Personal'
- For corporate R&D use, select 'Corporate R&D Professionals'
Subscribe:
Subscribe to ContraceptionAlready a print subscriber? Claim online access
Already an online subscriber? Sign in
Register: Create an account
Institutional Access: Sign in to ScienceDirect
References
- Ethnobotany and phytochemistry of yarrow, Achillea millefolium, Compositae.Econ Bot. 1982; 36: 203-223
- Plant materials used by primitive peoples to affect fertility.Science. 1954; 119: 626-631
- An examination of some reputed antifertility plants.Lloydia. 1975; 38: 135-140
- Antispermatogenic effects of 5-aminoindazole in rats.J Reprod Fertil. 1977; 50: 371-372
- Reversible changes in rat spermatogenesis induced by an antifertility substance (gossypol).Acta Histochem. 1985; 77: 185-191
- Effect of Trypterygium wilfordii on the fertility of rats.Contraception. 1986; 33: 105-110
- Effect of testosterone on the histological structure of the testis of adult albino rats.Indian J Med Res. 1973; 61: 1207-1211
- The effect of vinblastine sulfate on rat spermatogenesis.Arch Biol. 1974; 85: 353-364
- Antimalarial activity of some natural peroxides.Planta Med. 1991; 57: 295-296
- Fine structure of mouse testes following intraperitoneal treatment with 5-thio-D-glucose.J Heredity. 1979; 70: 194-198
Article info
Publication history
Accepted:
September 21,
1998
Received in revised form:
September 21,
1998
Received:
January 9,
1998
Identification
Copyright
© 1998 Elsevier Science Inc. Published by Elsevier Inc. All rights reserved.
